Rodríguez-Castillejo, Paula M.Fernández-de-las-Peñas, CésarAlburquerque-Sendín, FranciscoRodrigues-de-Souza, Daiana P.2022-12-232022-12-232021-10-18Rodríguez-Castillejo PM, Fernández-de-Las-Peñas C, Alburquerque-Sendín F, Rodrigues-de-Souza DP. Is Irritable Bowel Syndrome Considered as Comorbidity in Clinical Trials of Physical Therapy Interventions in Fibromyalgia? A Scoping Review. J Clin Med. 2021 Oct 18;10(20):4776http://hdl.handle.net/10668/4544Evidence supports the presence of comorbid conditions, e.g., irritable bowel syndrome (IBS), in individuals with fibromyalgia (FM). Physical therapy plays an essential role in the treatment of FM; however, it is not currently known whether the IBS comorbidity is considered in the selection criteria for clinical trials evaluating physiotherapy in FM. Thus, the aim of the review was to identify whether the presence of IBS was considered in the selection criteria for study subjects for those clinical trials that have been highly cited or published in the high-impact journals investigating the effects of physical therapy in FM. A literature search in the Web of Science database for clinical trials that were highly cited or published in high-impact journals, i.e., first second quartile (Q1) of any category of the Journal Citation Report (JCR), investigating the effects of physical therapy in FM was conducted. The methodological quality of the selected trials was assessed with the Physiotherapy Evidence Database (PEDro) scale. Authors, affiliations, number of citations, objectives, sex/gender, age, and eligibility criteria of each article were extracted and analyzed independently by two authors. From a total of the 412 identified articles, 20 and 61 clinical trials were included according to the citation criterion or JCR criterion, respectively. The PEDro score ranged from 2 to 8 (mean: 5.9, SD: 0.1). The comorbidity between FM and IBS was not considered within the eligibility criteria of the participants in any of the clinical trials. The improvement of the eligibility criteria is required in clinical trials on physical therapy that include FM patients to avoid selection bias.enAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/FibromyalgiaIrritable bowel syndromeClinical trialsPhysiotherapyEligibility criteriaFibromialgiaSíndrome del colon irritableEnsayos clínicos como asuntoEspecialidad de fisioterapiaDeterminación de la elegibilidadRevisiónMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Diseases::Musculoskeletal Diseases::Muscular Diseases::FibromyalgiaMedical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Colonic Diseases::Colonic Diseases, Functional::Irritable Bowel SyndromeMedical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Bias (Epidemiology)::Selection BiasMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Methods::Research Design::Patient SelectionMedical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Factors::ComorbidityMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Physical Therapy ModalitiesMedical Subject Headings::Information Science::Information Science::Communications Media::Publications::Serial Publications::Periodicals as TopicMedical Subject Headings::Publication Type::Publication Formats::Journal Article::Reviewreview article34682899Acceso abierto10.3390/jcm102047762077-0383PMC8541581