Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper

Hox, ValerieLourijsen, EvelijnJordens, ArnoutAasbjerg, KristianAgache, IoanaAlobid, IsamBachert, ClausBoussery, KoenCampo, PalomaFokkens, WytskeHellings, PeterHopkins, ClaireKlimek, LudgerMäkelä, MikaMösges, RalphMullol, JoaquimPujols, LauraRondon, CarmenRudenko, MichaelToppila-Salmi, SannaScadding, GlenisScheire, SophieTomazic, Peter-ValentinVan Zele, ThibautWagemann, Martinvan Boven, Job F. M.Gevaert, Philippe2022-06-222022-06-222020-01-03Hox V, Lourijsen E, Jordens A, Aasbjerg K, Agache I, Alobid I, et al. Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper. Clin Transl Allergy. 2020 Jan 3;10:1http://hdl.handle.net/10668/3699Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that-potentially severe-side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.enAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/GlucocorticosteroidsRhinitisRhinosinusitisGlucocorticoidesRinitisSinusitisPólipos nasalesCorticoesteroidesMedical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Adrenal Cortex HormonesMedical Subject Headings::Diseases::Otorhinolaryngologic Diseases::Nose Diseases::RhinitisMedical Subject Headings::Diseases::Otorhinolaryngologic Diseases::Nose Diseases::Paranasal Sinus Diseases::SinusitisMedical Subject Headings::Diseases::Otorhinolaryngologic Diseases::Nose Diseases::Nasal PolypsMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Adrenal Cortex Hormones::GlucocorticoidsBenefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paperreview article31908763open access10.1186/s13601-019-0303-62045-7022PMC6941282