Prevalence of Electrocardiographic Patterns Associated With Sudden Cardiac Death in the Spanish Population Aged 40 Years or Older. Results of the OFRECE Study.

Awamleh García, PaulaAlonso Martín, Joaquín JesúsGraupner Abad, CatherineJiménez Hernández, Rosa MaríaCurcio Ruigómez, AlejandroTalavera Calle, PedroCristóbal Varela, CarmenSerrano Antolín, JoséMuñiz, JavierGómez Doblas, Juan JoséRoig, Eulaliainvestigators of the OFRECE study2023-01-252023-01-252017-03-28http://hdl.handle.net/10668/11032Some electrocardiographic patterns are associated with an increased risk of sudden cardiac death due to ventricular arrhythmias. There is no information on the prevalence of these patterns in the general population in Spain. The objective of this study was to analyze the prevalence of these patterns and associated clinical and epidemiological factors. This subanalysis of the OFRECE study selected a representative sample of the Spanish population aged ≥ 40 years. We studied the presence or absence of electrocardiographic patterns of Brugada syndrome and QT interval abnormalities. Clinical data and electrocardiograms were available in all participants. Electrocardiograms were evaluated by 2 cardiologists and a third cardiologist was consulted if there was disagreement in the diagnosis. We calculated the weighted prevalence and clinical factors associated with the presence of Brugada-type patterns or QT segment abnormalities. Overall, 8343 individuals were evaluated (59.2 years, 52.4% female). There were 12 Brugada cases (type 1, 2 cases; type 2, 10 cases; weighted prevalence, 0.13%). For corrected QT (QTc) analysis, we excluded participants with left bundle branch block or without sinus rhythm. Weighted prevalences were as follows: short QTc ( A total of 0.6% to 1.1% of the Spanish population aged ≥ 40 years has an electrocardiographic pattern associated with a higher risk of sudden death (Brugada syndrome, long QT, or short QT).enAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/EpidemiologyEpidemiologíaLong QT syndromeMuerte súbitaSudden deathSíndrome de QT largoTachyarrhythmiasTaquiarritmiasAdultAgedAged, 80 and overArrhythmias, CardiacBrugada SyndromeDeath, Sudden, CardiacElectrocardiographyFemaleHumansLong QT SyndromeMaleMiddle AgedPrevalenceRisk FactorsSpainPrevalence of Electrocardiographic Patterns Associated With Sudden Cardiac Death in the Spanish Population Aged 40 Years or Older. Results of the OFRECE Study.research article28363711open access10.1016/j.rec.2016.11.0391885-5857https://ruc.udc.es/dspace/bitstream/2183/19590/3/Awamleh_Prevalence.pdf