Isla, DoloresFelip, EnriquetaViñolas, NuriaProvencio, MarianoMajem, MargaritaArtal, AngelBover, IsabelLianes, PilarDE Las Peñas, RamónCatot, SilviaDE Castro, JavierBlasco, AnaTerrasa, JosefaGonzalez-Larriba, José LuisJuan, OscarDómine, ManuelBernabe, ReyesGarrido, Pilar2023-01-252023-01-252016http://hdl.handle.net/10668/10661The WORLD07 project is a female-specific database to prospectively analyze the characteristics of Spanish women with lung cancer. We analyzed and compared lung cancer features in women with and without a family history of cancer/lung cancer. Two thousand and sixty women were included: 876 had a family history of cancer (lung cancer, 34%) and 886 did not, with no significant differences between groups, except for smoking status (p=0.036). We found statistically significant correlations between epidermal growth factor receptor (EGFR) mutation and smoking status in patients with a family history of cancer (r=-0.211; p Among Spanish women with lung cancer, a greater proportion were current smokers in those with a family history of cancer/lung cancer. There was a significant correlation between the presence of EGFR mutation and smoking.enCancerSpanish womenWORLD07 databaseepidermal growth factor receptorfamily historylung cancer riskmenopausal statussmokingCarcinoma, Non-Small-Cell LungCarcinoma, Small CellErbB ReceptorsFemaleGenetic Predisposition to DiseaseHumansLung NeoplasmsSpainresearch article27919997open access10.21873/anticanres.112731791-7530http://ar.iiarjournals.org/content/36/12/6647.full.pdf