Resino, SalvadorJiménez-Sousa, María ÁngelesBlanco, JuliàPacheco, Yolanda MDel Romero, JorgePeraire, JoaquimVirseda-Berdices, AnaMuñoz-Gómez, María JoséGalera-Peñaranda, CarlosGarcía-Fraile, Lucio JesusBenito, José MRallón, Norma2023-05-032023-05-032022-01-181663-9812http://hdl.handle.net/10668/20699Background: The lack of the recovery of CD4+ T-cells (CD4+ recovery) among immunodeficiency virus (HIV)-infected patients on antiretroviral therapy (ART) is not well known. We aimed to analyze the association between single nucleotide polymorphisms (SNPs) underlying vitamin D metabolism and the CD4+ recovery in naïve HIV-infected patients who started ART with low baseline CD4+. Methods: We conducted a retrospective study in 411 naïve individuals with plasma HIV load >200 copies/mL and CD4+ 200 copies/mL and CD4+enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/CD4+ T cellsDBPDHCR7HIVSNPantiretroviral therapyimmune reconstitutionresearch article35115928open access10.3389/fphar.2021.773848PMC8804497https://www.frontiersin.org/articles/10.3389/fphar.2021.773848/pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804497/pdf