Alcántara Luna, SaraPeral Rubio, FranciscoPerea Cejudo, ManuelRios Martín, Juan JoséFerrándiz Pulido, LaraCamacho-Martinez, Francisco2015-12-032015-12-032015-03Luna SA, Rubio FP, Cejudo MP, Rios Martín JJ, Pulido LF, Camacho-Martinez F. Cutaneous leishmaniasis mimicking a pyogenic granuloma. Acta Derm. Venereol.. 2015 ; 95(3):357-80001-5555http://hdl.handle.net/10668/2103Case reportThe Leishmania genus is formed by parasitic protozoa which are transmitted by the bite of infected female sand flies. Cases of sexual, vertical or transfusional transmission or via infected needles have also been described. In humans, 4 forms of this disease have been described: localised cutaneous (LC), diffuse cutaneous, mucocutaneous and visceral (1). LC counts for 50–75% of all cases (2), it is the mildest form of the disease and can be caused by any species of Leishmania. In Spain, the most frequent form is the oriental sore caused by L. infantum (2). Most cases resolve spontaneously within one year. In United States and Europe, the incidence is increasing due to tourism and co-infection with HIV. The morphological spectrum of LC is very wide; multiple forms of clinical presentation have been described, although the most characteristic one is the nodular ulcerative lesion, characterised by painless crater-like ulcers with a necrotic base and covered by an adhesive crust. The main complication of LC is its progression in some strains towards the other 3 forms of the disease (3). In patients with AIDS and other diseases associated with immunosuppression the risk of dissemination is much higher than in the immunocompetent. We present a case of LC with clinical and histopathological features similar to a pyogenic granuloma.enLeishmaniaSíndrome de inmunodeficiencia adquiridaCoinfecciónGranuloma piogénicoLeishmaniasis cutáneaMedical Subject Headings::Diseases::Virus Diseases::RNA Virus Infections::Retroviridae Infections::Lentivirus Infections::HIV Infections::Acquired Immunodeficiency SyndromeMedical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Specialty Uses of Chemicals::AdhesivesMedical Subject Headings::Organisms::Eukaryota::AnimalsMedical Subject Headings::Diseases::Bacterial Infections and Mycoses::Infection::CoinfectionMedical Subject Headings::Geographicals::Geographic Locations::EuropeMedical Subject Headings::Check Tags::FemaleMedical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Granuloma::Granuloma, PyogenicMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Immunomodulation::Immunotherapy::ImmunosuppressionMedical Subject Headings::Information Science::Information Science::Data Collection::Vital Statistics::Morbidity::IncidenceMedical Subject Headings::Organisms::Eukaryota::Euglenozoa::Kinetoplastida::Trypanosomatina::LeishmaniaMedical Subject Headings::Diseases::Parasitic Diseases::Protozoan Infections::Euglenozoa Infections::Leishmaniasis::Leishmaniasis, CutaneousMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::NeedlesMedical Subject Headings::Organisms::Eukaryota::Animals::Invertebrates::Arthropods::Insects::Diptera::PsychodidaeMedical Subject Headings::Geographicals::Geographic Locations::Europe::SpainMedical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::UlcerMedical Subject Headings::Geographicals::Geographic Locations::Americas::North America::United Statesresearch article24923493open access10.2340/00015555-19101651-2057