Casas-Barragán, AntonioMolina, FranciscoTapia-Haro, Rosa MaríaGarcía-Ríos, María CarmenCorrea-Rodríguez, MaríaAguilar-Ferrándiz, María Encarnación2022-09-132022-09-132021Casas-Barragán A, Molina F, Tapia-Haro RM, García-Ríos MC, Correa-Rodríguez M, Aguilar-Ferrándiz ME. Association of core body temperature and peripheral blood flow of the hands with pain intensity, pressure pain hypersensitivity, central sensitization, and fibromyalgia symptoms. Ther Adv Chronic Dis. 2021 Mar 5;12:20406223219972532040-6223http://hdl.handle.net/10668/4047Our aim was to analyse body core temperature and peripheral vascular microcirculation at skin hypothenar eminence of the hands and its relationship to symptoms in fibromyalgia syndrome (FMS). A total of 80 FMS women and 80 healthy women, matched on weight, were enrolled in this case-control study. Thermography and infrared thermometer were used for evaluating the hypothenar regions and core body temperature, respectively. The main outcome measures were pain pressure thresholds (PPTs) and clinical questionnaires. Significant associations were observed between overall impact [β = 0.033; 95% confidence interval (95%CI) = 0.003, 0.062; p = 0.030], daytime dysfunction (β = 0.203; 95%CI = 0.011, 0.395; p = 0.039) and reduced activity (β = 0.045; 95%CI = 0.005, 0.085; p = 0.029) and core body temperature in FMS women. PPTs including greater trochanter dominant (β = 0.254; 95%CI = 0.003, 0.504; p = 0.047), greater trochanter non-dominant (β = 0.650; 95%CI = 0.141, 1.159; p = 0.013), as well as sleeping medication (β = -0.242; 95%CI = -0.471, -0.013; p = 0.039) were also associated with hypothenar eminence temperature. Data highlighted that FMS women showed correlations among body core temperature and hand temperature with the clinical symptoms.enAtribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/Central sensitizationCore body temperatureFibromyalgiaPeripheral nervous systemPain pressure thresholdSymptomsThermographySensibilización del sistema nervioso centralTemperatura corporalFibromialgiaSistema nervioso periféricoUmbral del dolorSignos y síntomasTermografíaMedical Subject Headings::Check Tags::FemaleMedical Subject Headings::Diseases::Musculoskeletal Diseases::Muscular Diseases::FibromyalgiaMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control StudiesMedical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Body Temperature ChangesMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Confidence IntervalsMedical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Cardiovascular Physiological Processes::Blood Circulation::MicrocirculationMedical Subject Headings::Phenomena and Processes::Physical Phenomena::Thermodynamics::TemperatureMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::ThermographyMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::ThermometersMedical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Science::Research::Biomedical Research::Outcome Assessment (Health Care)Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Nervous System Physiological Phenomena::Nervous System Physiological Processes::Sensation::Pain::Pain Thresholdresearch article33747428Acceso abierto10.1177/20406223219972532040-6231PMC7940732