Grilo, IsraelPascasio, Juan ManuelTirado, Juan LuisLopez-Pardo, Francisco-JesusOrtega-Ruiz, FranciscoSousa, Jose ManuelRodriguez-Puras, Maria JoseFerrer, Maria TeresaGomez-Bravo, Miguel AngelGrilo Reina, Antonio2023-01-252023-01-252017-05Grilo I, Pascasio JM, Tirado JL, López-Pardo FJ, Ortega-Ruiz F, Sousa JM, et al. The utility of the macro-aggregated albumin lung perfusion scan in the diagnosis and prognosis of hepatopulmonary syndrome in cirrhotic patients candidates for liver transplantation. Rev Esp Enferm Dig. 2017 May;109(5):335-343.1130-0108http://hdl.handle.net/10668/10967The macro-aggregated albumin lung perfusion scan (99mTc-MAA) is a diagnostic method for hepatopulmonary syndrome (HPS). To determine the sensitivity of 99mTc-MAA in diagnosing HPS, to establish the utility of 99mTc-MAA in determining the influence of HPS on hypoxemia in patients with concomitant pulmonary disease and to determine the correlation between 99mTc-MAA values and other respiratory parameters. Data from 115 cirrhotic patients who were eligible for liver transplantation (LT) were prospectively analyzed. A transthoracic contrast echocardiography and 99mTc-MAA were performed in 85 patients, and 74 patients were diagnosed with HPS. The overall sensitivity of 99mTc-MAA for the diagnosis of HPS was 18.9% (14/74) in all of the HPS cases and 66.7% (4/6) in the severe to very severe cases. In HPS patients who did not have lung disease, the degree of brain uptake of 99mTc-MAA was correlated with the alveolar-arterial oxygen gradient (A-a PO2) (r = 0.32, p The 99mTc-MAA is a low sensitivity test for the diagnosis of HPS that can be useful in patients who have concomitant lung disease and in severe to very severe cases of HPS. It was not related to mortality, and brain uptake normalized after LT.enHepatopulmonary syndromeLung perfusion scanTechnetium Tc 99m macroaggregated albuminHypoxemiaLiver transplantationPulmonary diseaseAdultAlbuminsEchocardiographyFemaleFollow-Up StudiesHepatopulmonary SyndromeHumansHypoxiaLiver CirrhosisLiver TransplantationLungMaleMiddle AgedOrganotechnetium CompoundsPreoperative CarePrognosisProspective StudiesRadionuclide ImagingRadiopharmaceuticalsSensitivity and SpecificitySeverity of Illness IndexSurvival Rateresearch article28301945Restricted AccessSíndrome hepatopulmonarGammagrafía de perfusión pulmonarAlbúmina macroagregada marcada con tecnecio Tc 99mHipoxemiaTrasplante de hígadoEnfermedades pulmonares10.17235/reed.2017.4219/2016https://doi.org/10.17235/reed.2017.4219/2016