Rodríguez Lara, AvileneMesa-García, María DoloresMedina, Karla Alejandra DamiánQuirantes Piné, RosaCasuso, Rafael A.Segura Carretero, AntonioHuertas, Jesús Rodríguez2023-01-112023-01-112021-12-04Rodríguez Lara A, Mesa-García MD, Medina KAD, Quirantes Piné R, Casuso RA, Segura Carretero A, et al. Assessment of the Phytochemical and Nutrimental Composition of Dark Chia Seed (Salvia hispánica L.). Foods. 2021 Dec 4;10(12):3001http://hdl.handle.net/10668/4566Chia seeds are rich sources of different macro and micronutrients associated with health benefits; thus, they may be considered as a functional food. However, the composition depends on the variety, origin, climate and soil. Here, we show a comprehensive characterization of extractable and non-extractable phenolic compounds of dark chia seed Salvia hispanica L. using high-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight (HPLC-ESI-QTOF) and discuss potential health benefits associated with the presence of a number of nutritional and bioactive compounds. We report that dark chia from Jalisco is a high-fiber food, containing omega-3 polyunsaturated fatty acids, essential amino acids (phenylalanine and tryptophan), and nucleosides (adenosine, guanidine and uridine), and rich in antioxidant phenolic compounds, mainly caffeic acid metabolites. Our data suggest that chia seeds may be used as ingredients for the development of functional foods and dietary supplements.enAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/Chia seedFunctional foodFiberOmega-3Polyunsaturated fatty acidsEssential amino acidsNucleosidesPhenolic compoundsSemillasSalvia hispanicaAlimentos funcionalesFibras de la dietaÁcidos grasos Omega-3Ácidos grasos insaturadosAminoácidos esencialesNucleósidosCompuestos fenólicosMedical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::AntioxidantsMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, EssentialMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Chromatography::Chromatography, Liquid::Chromatography, High Pressure LiquidMedical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::NucleosidesMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Mass Spectrometry::Spectrometry, Mass, Electrospray IonizationMedical Subject Headings::Anatomy::Plant Structures::Plant Components, Aerial::Fruit::SeedsMedical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated::Fatty Acids, Omega-3Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Growth Substances::MicronutrientsMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, Essential::Phenylalanineresearch article34945556Acceso abierto10.3390/foods101230012304-8158PMC8702123