Radin, M.Schreiber, K.Cecchi, I.Signorelli, F.De Jesus, G.Aso, K.Kono, M.Urban, M. L.Bacco, B.Cassarino, S. GalloLo Sardo, L.Foddai, S. G.Barinotti, A.Garcia, I. GomezQuaglia, M. I.Tissera, Y.Gervasoni, F.Aguirre-Zamorano, M. A.Alba, P.Benedetto, C.Atsumi, T.Amengual, O.Emmi, G.Andrade, D.Marozio, L.Roccatello, D.Sciascia, S.2023-05-032023-05-032022-06-01Radin M, Schreiber K, Cecchi I, Signorelli F, De Jesùs G, Aso K, et al. AB0458 DISEASE ACTIVITY AT CONCEPTION PREDICTS LUPUS FLARE UP TO 2 YEARS AFTER BIRTH: a MULTICENTRE LONG TERM FOLLOW-UP STUDY. Annals Of The Rheumatic Diseases [Internet]. 23 de mayo de 2022;81(Suppl 1):1356-70003-4967http://hdl.handle.net/10668/20056Background: Systemic lupus erythematosus (SLE) often affects women in their childbearing years, and pregnancy may affect SLE disease activity during pregnancy and post-partum (1,2). Limited data assessing the likelihood and characteristics of SLE activity in an extended time period post-partum which may be relevant as patients may wish further pregnancies exist. Objectives: To assess predicting factors that might influence SLE disease activity in women in an extended follow-up period of 2 years after giving birth and clinical assessment every three months. Methods: The study was design as an international retrospective, data-driven case collection study, enrolling 119 women with a first birth and with a strictly monitored follow-up period of 2 years.enLupus erythematosus, systemicPostpartum periodFollow-up studiesPregnancy outcomeHumansPregnancyFemaleRetrospective studiesBirth orderconference outputopen accessEmbarazoEstudios retrospectivosFemeninoHumanosOrden de nacimiento10.1136/annrheumdis-2022-eular.7651468-2060https://ard.bmj.com/content/annrheumdis/81/Suppl_1/1356.full.pdf850279005314