Zozaya, NéboaVilloro, RenataAbdalla, FernandoAlfonso Zamora, SantiagoBalea Filgueiras, JesúsCarrascosa Carrillo, José ManuelDelgado Sánchez, OlgaDolz Sinisterra, FranciscoGarcía-Ruiz, AntonioHerranz Pinto, PedroManfredi, AntonioMartínez Olmos, JoséMorales de Los Ríos Luna, PalomaPuig Sanz, LluisRos, SandraHildago-Vega, Álvaro2023-05-032023-05-032022-03-25http://hdl.handle.net/10668/20502Psoriasis is a chronic, systemic inflammatory disease that affects the skin, with a high impact on patients' quality of life. The aim of this study was to identify and determine the relative importance of unmet needs in the management of moderate-to-severe psoriasis in Spain, from a multi-stakeholder perspective. A mixed method-approach was used to collect information, design a questionnaire and a discrete-choice exercise, and elicit the unmet needs through a multidisciplinary committee composed of 12 experts. A total of 65 unmet needs were identified and categorized into 4 areas: clinical, patient-related, decision-making process, and social. Decision-making process unmet needs were perceived as the most pressing ones, followed by social, clinical and patient-related. Individually, the need to incorporate outcomes that are important to the patients and to have treatments that achieve total clearance with a rapid onset of action and long-term persistence were the most important unmet needs.enAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/ExerciseHumansPsoriasisQuality of LifeSpainSurveys and Questionnairesresearch article35312022open access10.2340/actadv.v102.5831651-2057PMC9631248https://medicaljournalssweden.se/actadv/article/download/583/3251https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631248/pdf