Gomez, AntonioRus, GuillermoSaffari, Nader2022-09-262022-09-262021-04-15Gomez A, Rus G, Saffari N. Wave Propagation in a Fractional Viscoelastic Tissue Model: Application to Transluminal Procedures. Sensors. 2021 Apr 15;21(8):2778http://hdl.handle.net/10668/4134In this article, a wave propagation model is presented as the first step in the development of a new type of transluminal procedure for performing elastography. Elastography is a medical imaging modality for mapping the elastic properties of soft tissue. The wave propagation model is based on a Kelvin Voigt Fractional Derivative (KVFD) viscoelastic wave equation, and is numerically solved using a Finite Difference Time Domain (FDTD) method. Fractional rheological models, such as the KVFD, are particularly well suited to model the viscoelastic response of soft tissue in elastography. The transluminal procedure is based on the transmission and detection of shear waves through the luminal wall. Shear waves travelling through the tissue are perturbed after encountering areas of altered elasticity. These perturbations carry information of medical interest that can be extracted by solving the inverse problem. Scattering from prostate tumours is used as an example application to test the model. In silico results demonstrate that shear waves are satisfactorily transmitted through the luminal wall and that echoes, coming from reflected energy at the edges of an area of altered elasticity, which are feasibly detectable by using the transluminal approach. The model here presented provides a useful tool to establish the feasibility of transluminal procedures based on wave propagation and its interaction with the mechanical properties of the tissue outside the lumen.enAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/Transluminal elastographyShear waveFractional viscoelasticityKelvin voigt fractional derivativeFinite differenceElastografíaOnda SElasticidadAnálisis de elementos finitosMedical Subject Headings::Information Science::Information Science::Computing Methodologies::Computer SimulationMedical Subject Headings::Phenomena and Processes::Physical Phenomena::Mechanical Phenomena::ElasticityMedical Subject Headings::Check Tags::MaleMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Phantoms, ImagingMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::RheologyMedical Subject Headings::Phenomena and Processes::Chemical Phenomena::Physicochemical Phenomena::ViscosityMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Ultrasonography::Elasticity Imaging Techniquesresearch article33920801Acceso abierto10.3390/s210827781424-8220PMC8071186