Wangüemert-Pérez, J. GonzaloHadij-ElHouati, AbdelfettahSánchez-Postigo, AlejandroLeuermann, JonasXu, Dan-XiaCheben, PavelOrtega-Moñux, AlejandroHalir, RobertMolina-Fernández, Íñigo2021-05-282021-05-282018-08-23Wangüemert-Pérez JG, Hadij-ElHouati A, Sánchez-Postigo A, Leuermann J, Xu D-X, Cheben P, et al. [INVITED] Subwavelength structures for silicon photonics biosensing. Optics & Laser Technology. 2019;109:437–448.0030-3992http://hdl.handle.net/10668/3343Silicon photonic biosensors hold the potential for highly accurate, yet low cost point-of-care devices. Maximizing the sensitivity of the sensing chips while reducing the complexity and cost of the read-out system is pivotal to realize this potential. Here we present an extensive analysis, both from a practical and a theoretical perspective, of current biosensors, and analyze how subwavelength structures can be exploited to enhance their sensitivity. This study is not restricted just to the near-infrared band as we also determine the sensing capabilities of the suspended silicon waveguides with subwavelength metamaterial cladding working in the mid-infrared range. These waveguides have been recently proposed to cover the full transparency window of silicon (λ < 8.5 μm), where the fingerprint spectral region of many molecules takes place and so a plethora of evanescent field absorption-based applications will be developed in the near future.enSubwavelength waveguidesSilicon photonicsBiosensorsCoherent multi-port sensing architectureMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Molecular Probe Techniques::Biosensing TechniquesMedical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Elements::Metalloids::SiliconMedical Subject Headings::Health Care::Health Services Administration::Patient Care Management::Point-of-Care SystemsMedical Subject Headings::Phenomena and Processes::Physical Phenomena::Magnetic Phenomena::Electromagnetic Phenomena::Electromagnetic Radiation::Light::PhotonsMedical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Pigmentation DisordersMedical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Skin Abnormalitiesresearch articleAcceso abierto10.1016/j.optlastec.2018.07.071