Cruz, RaquelDiz-de Almeida, SilviaLopez de Heredia, MiguelQuintela, InesCeballos, Francisco CPita, GuillermoLorenzo-Salazar, Jose MGonzalez-Montelongo, RafaelaGago-Dominguez, ManuelaSevilla Porras, MartaTenorio Castaño, Jair AntonioNevado, JulianAguado, Jose MaríaAguilar, CarlosAguilera-Albesa, SergioAlmadana, VirginiaAlmoguera, BertaAlvarez, NuriaAndreu-Bernabeu, AlvaroArana-Arri, EunateArango, CelsoArranz, Maria JArtiga, Maria-JesusBaptista-Rosas, Raul CBarreda-Sanchez, MariaBelhassen-Garcia, MoncefBezerra, Joao FBezerra, Marcos A CBoix-Palop, LuciaBrion, MariaBrugada, RamonBustos, MatildeCalderon, Enrique JCarbonell, CristinaCastano, LuisCastelao, Jose EConde-Vicente, RosaCordero-Lorenzana, M LourdesCortes-Sanchez, Jose LCorton, MartaDarnaude, M TeresaDe Martino-Rodriguez, AlbaDel Campo-Perez, VictorDiaz de Bustamante, AranzazuDominguez-Garrido, ElenaLuchessi, Andre DEiros, RocioEstigarribia Sanabria, Gladys MercedesCarmen Fariñas, MariaFernandez-Robelo, UxiaFernandez-Rodriguez, AmandaFernandez-Villa, TaniaGil-Fournier, BelenGomez-Arrue, JavierGonzalez Alvarez, BeatrizGonzalez Bernaldo de Quirós, FernanGonzalez-Peñas, JavierGutierrez-Bautista, Juan FHerrero, Maria JoseHerrero-Gonzalez, AntonioJimenez-Sousa, Maria ALattig, Maria ClaudiaLiger Borja, AnabelLopez-Rodriguez, RosarioMancebo, EstherMartin-Lopez, CaridadMartín, VicenteMartinez-Nieto, OscarMartinez-Lopez, IciarMartinez-Resendez, Michel FMartinez-Perez, AngelMazzeu, Juliana FMerayo Macias, EleuterioMinguez, PabloMoreno Cuerda, VictorSilbiger, Vivian NOliveira, Silviene FOrtega-Paino, EvaParellada, MaraPaz-Artal, EstelaSantos, Ney P CPerez-Matute, PatriciaPerez, PatriciaPerez-Tomas, M ElenaPerucho, TeresaPinsach-Abuin, Mel LinaPompa-Mera, Ericka NPorras-Hurtado, Gloria LPujol, AuroraRamiro Leon, SorayaResino, SalvadorFernandes, Marianne RRodriguez-Ruiz, EmilioRodriguez-Artalejo, FernandoRodriguez-Garcia, Jose ARuiz Cabello, FranciscoRuiz-Hornillos, JavierRyan, PabloSoria, Jose ManuelSouto, Juan CarlosTamayo, EduardoTamayo-Velasco, AlvaroTaracido-Fernandez, Juan CarlosTeper, AlejandroTorres-Tobar, LilianUrioste, MiguelValencia-Ramos, JuanYáñez, ZuleimaZarate, RuthNakanishi, TomokoPigazzini, SaraDegenhardt, FraukeButler-Laporte, GuillaumeMaya-Miles, DouglasBujanda, LuisBouysran, YoussefPalom, AdrianaEllinghaus, DavidMartínez-Bueno, ManuelRolker, SelinaAmitrano, SaraRoade, LuisaFava, FrancescaSpinner, Christoph DPrati, DanieleBernardo, DavidGarcia, FedericoDarcis, GillesFernandez-Cadenas, IsraelHolter, Jan CatoBanales, Jesus MFrithiof, RobertDuga, StefanoAsselta, RosannaPereira, Alexandre CRomero-Gomez, ManuelNafria-Jimenez, BeatrizHov, Johannes RMigeotte, IsabelleRenieri, AlessandraPlanas, Anna MLudwig, Kerstin UButi, MariaRahmouni, SouadAlarcon-Riquelme, Marta ESchulte, Eva CFranke, AndreKarlsen, Tom HValenti, LucaZeberg, HugoRichards, BrentGanna, AndreaBoada, Mercede Rojas, ItziarRuiz, AgustinSanchez-Juan, PascualReal, Luis MiguelGuillen-Navarro, EncarnaAyuso, CarmenGonzalez-Neira, AnnaRiancho, Jose ARojas-Martinez, AugustoFlores, CarlosLapunzina, PabloCarracedo, Angel2023-05-032023-05-032022-06-01Cruz R, Diz-de Almeida S, López de Heredia M, Quintela I, Ceballos FC, Pita G, et al. Novel genes and sex differences in COVID-19 severity. Hum Mol Genet. 2022 Nov 10;31(22):3789-3806.http://hdl.handle.net/10668/19788Here, we describe the results of a genome-wide study conducted in 11 939 coronavirus disease 2019 (COVID-19) positive cases with an extensive clinical information that were recruited from 34 hospitals across Spain (SCOURGE consortium). In sex-disaggregated genome-wide association studies for COVID-19 hospitalization, genome-wide significance (P enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/HumansGenome-Wide Association StudySex CharacteristicsFemaleMaleMiddle AgedPolymorphism, Single NucleotideCOVID-19Genetic LociGenetic Predisposition to DiseaseNovel genes and sex differences in COVID-19 severity.research article35708486open accessFemeninoMasculinoPersona de mediana edadPolimorfismo de nucleótido simplePredisposición genética a la enfermedadSitios genéticos10.1093/hmg/ddac1321460-2083PMC9652109https://academic.oup.com/hmg/advance-article-pdf/doi/10.1093/hmg/ddac132/45437987/ddac132.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652109/pdf