Enrique, Pérez-Cuadrado RoblesPilar, Esteban DelgadoPaloma, Bebia ConesaBlanca, Martínez AndrésFranulic, Milivoj GuggianaEduardo, Alcaraz MateosMariana, Fernández CaballeroJosé Luis, Rodrigo AgudoSilvia, Chacón MartínezRafael, LatorreFederico, SoriaJuan Manuel, Herrerías GutiérrezEnrique, Pérez-Cuadrado Martínez2016-03-072016-03-072015-06-10Robles EP, Delgado PE, Conesa PB, Andrés BM, Guggiana MF, Mateos EA, et al. Role of double-balloon enteroscopy in malignant small bowel tumors. World J Gastrointest Endosc. 2015; 7(6):652-8http://hdl.handle.net/10668/2154Journal Article;AIMTo assess the double-balloon enteroscopy (DBE) role in malignant small bowel tumors (MSBT). METHODS This is a retrospective descriptive study performed in a single center. All consecutive patients who underwent a DBE with final diagnosis of a malignant neoplasm from 2004 to 2014 in our referral center were included. Patient demographic and clinical pathological characteristics were recorded and reviewed. MSBT diagnosis was achieved either by DBE directed biopsy with multiple tissue sampling, endoscopic findings or histological analysis of surgical specimen. We have analyzed double-balloon enteroscopy impact in outcome and clinical course of these patients. RESULTS Of 627 patients, 28 (4.5%) (mean age = 60 ± 17.3 years) underwent 30 procedures (25 anterograde, 5 retrograde) and were diagnosed of a malignant tumor. Patients presented with obscure gastrointestinal bleeding (n = 19, 67.9%), occlusion syndrome (n = 7, 25%) and diarrhea (n = 1, 3.6%). They were diagnosed by DBE biopsy (n = 18, 64.3%), histological analysis of surgical specimen (n = 7, 25%) and unequivocal endoscopic findings (n = 2, 7.1%). Gastrointestinal stromal tumor (n = 8, 28.6%), adenocarcinoma (n = 7, 25%), lymphoma (n = 4, 14.3%), neuroendocrine tumor (n = 4, 14.3%), metastatic (n = 3, 10.7%) and Kaposi sarcoma (n = 1, 3.6%) were identified. DBE modified outcome in 7 cases (25%), delaying or avoiding emergency surgery (n = 3), modifying surgery approach (n = 2) and indicating emergency SB partial resection instead of elective approach (n = 2). CONCLUSION DBE may be critical in the management of MSBT providing additional information that may be decisive in the clinical course of these patients.enDouble balloon enteroscopyMalignant small bowel tumorsObscure gastrointestinal bleedingGastrointestinal stromal tumorOcclusion syndromeAdenocarcinomaEnteroscopía de doble BalónHemorragia gastrointestinalIntestino delgadoTumores neuroendocrinosSarcoma de KaposiMedical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Glandular and Epithelial::Carcinoma::AdenocarcinomaMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Cytological Techniques::Cytodiagnosis::BiopsyMedical Subject Headings::Disciplines and Occupations::Social Sciences::DemographyMedical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Signs and Symptoms, Digestive::DiarrheaMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Surgical::Endoscopy::Endoscopy, Digestive System::Endoscopy, Gastrointestinal::Double-Balloon EnteroscopyMedical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases::Gastrointestinal HemorrhageMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Anatomy::Digestive System::Gastrointestinal Tract::Intestines::Intestine, SmallMedical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::LymphomaMedical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Germ Cell and Embryonal::Neuroectodermal Tumors::Neuroendocrine TumorsMedical Subject Headings::Health Care::Health Services Administration::Organization and Administration::Professional Practice::Referral and ConsultationMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies::Retrospective StudiesMedical Subject Headings::Diseases::Virus Diseases::DNA Virus Infections::Herpesviridae Infections::Sarcoma, Kaposiresearch article26078833open access10.4253/wjge.v7.i6.6521948-5190PMC4461939