Jesús, SLabrador-Espinosa, M AAdarmes, A DMéndel-Del Barrio, CMartínez-Castrillo, J CAlonso-Cánovas, ASánchez Alonso, PNovo-Ponte, SAlonso-Losada, M GLópez Ariztegui, NSegundo Rodríguez, J CMorales, M IGastón, ILacruz Bescos, FClavero Ibarra, PKulisevsky, JPagonabarraga, JPascual-Sedano, BMartínez-Martín, PSantos-García, DMir, PCOPPADIS Study Group2023-02-092023-02-092020-10-09http://hdl.handle.net/10668/16389The study was aimed at analysing the frequency of impulse control disorders (ICDs) and compulsive behaviours (CBs) in patients with Parkinson's disease (PD) and in control subjects (CS) as well as the relationship between ICDs/CBs and motor, nonmotor features and dopaminergic treatment in PD patients. Data came from COPPADIS-2015, an observational, descriptive, nationwide (Spain) study. We used the validated Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease-Rating Scale (QUIP-RS) for ICD/CB screening. The association between demographic data and ICDs/CBs was analyzed in both groups. In PD, this relationship was evaluated using clinical features and treatment-related data. As result, 613 PD patients (mean age 62.47 ± 9.09 years, 59.87% men) and 179 CS (mean age 60.84 ± 8.33 years, 47.48% men) were included. ICDs and CBs were more frequent in PD (ICDs 12.7% vs. 1.6%, p enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Antidepressive AgentsCohort StudiesComorbidityCompulsive BehaviorCross-Sectional StudiesDisruptive, Impulse Control, and Conduct DisordersDopamineDopamine AgonistsFemaleFollow-Up StudiesHumansImpulsive BehaviorMaleMiddle AgedParkinson DiseaseQuality of LifeRisk FactorsSpainSurveys and QuestionnairesNon-motor symptom burden in patients with Parkinson's disease with impulse control disorders and compulsive behaviours: results from the COPPADIS cohort.research article33037247open access10.1038/s41598-020-73756-z2045-2322PMC7547680https://www.nature.com/articles/s41598-020-73756-z.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547680/pdf