Martinez-Garcia, AliciaNaranjo-Saucedo, Ana BelénRivas, Jose AntonioRomero Tabares, AntonioMarín Cassinello, AnaAndrés-Martín, AnselmoSánchez Laguna, Francisco JoséVillegas, RomanPérez León, Francisco De PaulaMoreno Conde, JesúsParra Calderón, Carlos Luis2022-07-262022-07-262021-03-10Martinez-Garcia A, Naranjo-Saucedo AB, Rivas JA, Romero Tabares A, Marín Cassinello A, Andrés-Martín A, et al. A Clinical Decision Support System (KNOWBED) to Integrate Scientific Knowledge at the Bedside: Development and Evaluation Study. JMIR Med Inform. 2021 Mar 10;9(3):e13182http://hdl.handle.net/10668/3829Background: The evidence-based medicine (EBM) paradigm requires the development of health care professionals’ skills in the efficient search of evidence in the literature, and in the application of formal rules to evaluate this evidence. Incorporating this methodology into the decision-making routine of clinical practice will improve the patients’ health care, increase patient safety, and optimize resources use. Objective: The aim of this study is to develop and evaluate a new tool (KNOWBED system) as a clinical decision support system to support scientific knowledge, enabling health care professionals to quickly carry out decision-making processes based on EBM during their routine clinical practice. Methods: Two components integrate the KNOWBED system: a web-based knowledge station and a mobile app. A use case (bronchiolitis pathology) was selected to validate the KNOWBED system in the context of the Paediatrics Unit of the Virgen Macarena University Hospital (Seville, Spain). The validation was covered in a 3-month pilot using 2 indicators: usability and efficacy. Results: The KNOWBED system has been designed, developed, and validated to support clinical decision making in mobility based on standards that have been incorporated into the routine clinical practice of health care professionals. Using this tool, health care professionals can consult existing scientific knowledge at the bedside, and access recommendations of clinical protocols established based on EBM. During the pilot project, 15 health care professionals participated and accessed the system for a total of 59 times. Conclusions: The KNOWBED system is a useful and innovative tool for health care professionals. The usability surveys filled in by the system users highlight that it is easy to access the knowledge base. This paper also sets out some improvements to be made in the future.enAtribución 4.0 InternacionalAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/Evidence-based medicineClinical decision support systemScientific knowledge integrationMedicina basada en la evidenciaSistemas de apoyo a decisiones clínicasConocimientoAndalucíaMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Persons::Persons::Age Groups::ChildMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Pilot ProjectsMedical Subject Headings::Information Science::Information Science::Medical Informatics::Medical Informatics Applications::Information Systems::Decision Support Systems, ClinicalMedical Subject Headings::Information Science::Information Science::Computing Methodologies::Software::Mobile ApplicationsMedical Subject Headings::Health Care::Environment and Public Health::Public Health::Accidents::Accident Prevention::Safety::Patient SafetyMedical Subject Headings::Geographical Locations::Geographic Locations::Europe::SpainMedical Subject Headings::Disciplines and Occupations::Health Occupations::Evidence-Based Practice::Evidence-Based MedicineMedical Subject Headings::Health Care::Health Care Facilities, Manpower, and Services::Health PersonnelMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Clinical ProtocolsMedical Subject Headings::Information Science::Information Science::Computing Methodologies::Artificial Intelligence::Knowledge BasesMedical Subject Headings::Diseases::Respiratory Tract Diseases::Bronchial Diseases::Bronchitis::BronchiolitisMedical Subject Headings::Health Care::Health Services Administration::Patient Care Management::Delivery of Health CareMedical Subject Headings::Geographical Locations::Geographic Locations::Europe::Spainresearch article33709932open access10.2196/131822291-9694PMC7991993