Maldonado-Araque, CristinaValdés, SergioLago-Sampedro, AnaLillo-Muñoz, Juan AntonioGarcia-Fuentes, EduardoPerez-Valero, VidalGutierrez-Repiso, CarolinaGoday, AlbertUrrutia, InesPeláez, LauraCalle-Pascual, AlfonsoCastaño, LuisCastell, ContxaDelgado, EliasMenendez, EdelmiroFranch-Nadal, JosepGaztambide, SoniaGirbés, JoanOrtega, EmilioVendrell, JoanChacón, Matilde RChaves, Felipe JSoriguer, FedericoRojo-Martínez, Gemma2023-01-252023-01-252018-04-26http://hdl.handle.net/10668/12403Previous studies have suggested that iron deficiency (ID) may impair thyroid hormone metabolism, however replication in wide samples of the general adult population has not been performed. We studied 3846 individuals free of thyroid disease, participants in a national, cross sectional, population based study representative of the Spanish adult population. Thyroid stimulating hormone (TSH), free thyroxin (FT4) and free triiodothyronine (FT3) were analyzed by electrochemiluminescence (E170, Roche Diagnostics). Serum ferritin was analyzed by immunochemiluminescence (Architect I2000, Abbott Laboratories). As ferritin levels decreased (>100, 30-100, 15-30, 100, 30-100, 15-30,enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/AdolescentAdultAgedAged, 80 and overAnemia, Iron-DeficiencyBiomarkersFemaleHumansHypothyroidismMaleMiddle AgedOdds RatioPopulation SurveillancePrevalenceRisk AssessmentRisk FactorsSpainThyroxineTriiodothyronineYoung Adultresearch article29700318open access10.1038/s41598-018-24352-92045-2322PMC5919900https://www.nature.com/articles/s41598-018-24352-9.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919900/pdf