Davila-Batista, VeronicaMolina, Antonio JVilorio-Marqués, LauraLujan-Barroso, Leilade Souza-Teixeira, FernandaOlmedo-Requena, RocíoArias de la Torre, JorgeGarcía-Martínez, LidiaÁlvarez-Álvarez, LauraFreisling, HeinzLlorca, JavierDelgado-Rodríguez, MiguelMartin, Vicente2023-01-252023-01-252018-06-11http://hdl.handle.net/10668/12648The CUN-BAE (Clínica Universidad de Navarra-Body adiposity estimator) index is an anthropometric index based on age, sex and body mass index (BMI) for a refined prediction of body fatness in adults. CUN-BAE may help detect metabolically unhealthy individuals with otherwise normal weight according to BMI or waist circumference (WC). The aim of this study was to evaluate whether CUN-BAE, independent of its components (BMI, age and sex), was associated with cardiometabolic conditions including arterial hypertension, diabetes mellitus and metabolic syndrome (MetS). The ENRICA study was based on a cross-sectional sample of non-institutionalized men and women representative of the adult Spanish population. Body weight, height, and WC were measured in all participants. The residual of CUN-BAE (rCUN-BAE), i.e. the part of the index not explained by its components, was calculated. The associations of CUN-BAE, rCUN-BAE, BMI and WC with hypertension, diabetes and MetS were analysed by multivariate logistic regression, and the Akaike information criterion (AIC) was calculated. The sample included 12,122 individuals. rCUN-BAE was associated with hypertension (OR 1.14, 95% CI 1.07-1.21) and MetS (OR 1.48, 1.37-1.60), but not with diabetes (OR 1.05, 0.94-1.16). In subjects with a BMI  The CUN-BAE index for body fatness was positively associated with hypertension, diabetes and MetS in adults independent of BMI or WC. CUN-BAE may help to identify individuals with cardiometabolic conditions beyond BMI, but this needs to be confirmed in prospective settings.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/BMIBody fatnessCUN-BAEDiabetesHypertensionMetabolic syndromeAdipose TissueAdolescentAdultAge FactorsAgedAged, 80 and overBody Mass IndexCross-Sectional StudiesDiabetes MellitusFemaleHumansHypertensionMaleMetabolic SyndromeMiddle AgedRisk FactorsSex FactorsSpainYoung Adultresearch article29948218open access10.1007/s00394-018-1743-91436-6215PMC6647072https://link.springer.com/content/pdf/10.1007/s00394-018-1743-9.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647072/pdf