Marcos-Delgado, AlbaFernández-Villa, TaniaMartínez-González, Miguel ÁngelSalas-Salvadó, JordiCorella, DoloresCastañer, OlgaMartínez, J. AlfredoAlonso-Gómez, Ángel M.Wärnberg, JuliaVioque, JesúsRomaguera, DoraLópez-Miranda, JoséEstruch, RamonTinahones, Francisco J.Lapetra, JoséSerra-Majem, J. LLuísGarcía-Molina, LauraTur, Josep A.de Paz, José AntonioPintó, XavierDelgado-Rodríguez, MiguelMatía-Martín, PilarVidal, JosepVázquez, ClotildeDaimiel, LidiaRos, EmilioBabio, NancyGimenez-Alba, Ignacio M.Toledo, EstefaníaZomeño, María DoloresZulet, M. A.Vaquero-Luna, JessicaPérez-López, JessicaPastor-Morel, AnaGalmes-Panades, Aina M.García-Rios, AntonioCasas, RosaBernal-López, María RosaSantos-Lozano, José ManuelBecerra-Tomás, NereaOrtega-Azorin, CarolinaVázquez-Ruiz, ZenaidaPérez-Vega, Karla AlejandraAbete, ItziarSorto-Sánchez, CarolinaPalau-Galindo, AntoniGalilea-Zabalza, IñigoMuñoz-Martínez, JúliaMartín, Vicente2022-11-212022-11-212020-05-25Marcos-Delgado A, Fernández-Villa T, Martínez-González MÁ, Salas-Salvadó J, Corella D, Castañer O, et al. The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome. Int J Environ Res Public Health. 2020 May 25;17(10):37281661-7827http://hdl.handle.net/10668/4368Los autores de este artículo forman parte el grupo de investigación PREDIMED-Plus.The main objective of this study was to examine the relationship between the level of physical activity (PA) and the degree of obesity with health-related quality of life (HRQoL) in individuals with metabolic syndrome (MetS) who participated in the Predimed-Plus study. A total of 6875 subjects between 55 and 75 years of age with MetS were selected and randomized in 23 Spanish centers. Subjects were classified according to categories of body mass index (BMI). PA was measured with the validated Registre Gironí del Cor (REGICOR) questionnaire and subjects were classified according to their PA level (light, moderate, vigorous) and the HRQoL was measured with the validated short-form 36 (SF-36) questionnaire. By using the ANOVA model, we found a positive and statistically significant association between the level of PA and the HRQoL (aggregated physical and mental dimensions p < 0.001), but a negative association with higher BMI in aggregated physical dimensions p < 0.001. Furthermore, women obtained lower scores compared with men, more five points in all fields of SF-36. Therefore, it is essential to promote PA and body weight control from primary care consultations to improve HRQoL, paying special attention to the differences that sex incurs.enAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/Health-related quality of lifePhysical activityObesityBody mass indexMetabolic syndromeCalidad de vidaEjercicio físicoObesidadÍndice de masa corporalSíndrome metabólicoMedical Subject Headings::Persons::Persons::Age Groups::Adult::AgedMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional StudiesMedical Subject Headings::Check Tags::FemaleMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Check Tags::MaleMedical Subject Headings::Persons::Persons::Age Groups::Adult::Middle AgedMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Anthropometry::Body Weights and Measures::Body Mass IndexMedical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Movement::Motor Activity::ExerciseMedical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance::Metabolic Syndrome XMedical Subject Headings::Anthropology, Education, Sociology and Social Phenomena::Social Sciences::Quality of LifeMedical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::ObesityMedical Subject Headings::Health Care::Health Services Administration::Patient Care Management::Comprehensive Health Care::Primary Health CareMedical Subject Headings::Health Care::Health Services Administration::Organization and Administration::Professional Practice::Referral and ConsultationMedical Subject Headings::Geographical Locations::Geographic Locations::Europe::Spainresearch article32466190open access10.3390/ijerph171037281660-4601PMC7277554