Monforte, VíctorUssetti, PiedadCastejón, RaquelSintes, HelenaPérez, Virginia LuzLaporta, RosalíaSole, AmparoCifrián, José ManuelMarcos, Pedro JRedel, JavierArcos, Ibai LosBerastegui, CristinaAlonso, RodrigoRosado, SilviaEscriva, JuanIturbe, DavidOvalle, Juan PabloVaquero, José ManuelLópez-Meseguer, ManuelMendoza, AlbertoGómez-Ollés, Susana2025-01-072025-01-072021-01-08https://hdl.handle.net/10668/25752Immune cell functional assay (ImmuKnow®) is a non-invasive method that measures the state of cellular immunity in immunosuppressed patients. We studied the prognostic value of the assay for predicting non-cytomegalovirus (CMV) infections in lung transplant recipients. A multicenter prospective observational study of 92 patients followed up from 6 to 12 months after transplantation was performed. Immune cell functional assay was carried out at 6, 8, 10, and 12 months. Twenty-three patients (25%) developed 29 non-CMV infections between 6 and 12 months post-transplant. At 6 months, the immune response was moderate (ATP 225-525ng/mL) in 14 (15.2%) patients and low (ATP Although ImmuKnow® does not seem useful to predict non-CMV infection, it could identify patients with a very low risk and help us define a target for an optimal immunosuppression.enImmuknowImmune cell assayImmunknowImmunosuppressionInfecciónInfectionInmunosupresiónLung transplantTest de inmunidad celularTrasplante pulmonarresearch article33551278open access10.1016/j.arbres.2020.12.0242173-5751https://doi.org/10.1016/j.arbres.2020.12.024