Fonte, LuisAcosta, ArmandoSarmiento, María ENorazmi, Mohd NorGinori, Maríade Armas, YaxsierCalderón, Enrique J2023-05-032023-05-032022-07-30http://hdl.handle.net/10668/21595There is an increasing attention to the emerging health problem represented by the clinical and functional long-term consequences of SARS-CoV-2 infection, referred to as postacute COVID-19 syndrome. Clinical, radiographic, and autopsy findings have shown that a high rate of fibrosis and restriction of lung function are present in patients who have recovered from COVID-19. Patients with active TB, or those who have recovered from it, have fibrotic scarred lungs and, consequently, some degree of impaired respiratory function. Helminth infections trigger predominantly type 2 immune responses and the release of regulatory and fibrogenic cytokines, such as TGF-β. Here, we analyze the possible consequences of the overlapping of pulmonary fibrosis secondary to COVID-19 and tuberculosis in the setting of sub-Saharan Africa, the region of the world with the highest prevalence of helminth infection.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/helminth coinfectionpostacute COVID-19 syndromepulmonary fibrosissub-Saharan Africatuberculosisresearch article36006249open access10.3390/tropicalmed70801572414-6366PMC9416620https://www.mdpi.com/2414-6366/7/8/157/pdf?version=1659316352https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416620/pdf