Sonnenschein, Eva C.Stierhof, MarcGoralczyk, StephanVabre, Floriane M.Pellissier, LeonieHanssen, Kine Ostnesde la Cruz, MercedesDiaz, Caridadde Witte, PeterCopmans, DanielleAndersen, Jeanette HammerHansen, EspenKristoffersen, VenkeTormo, Jose R.Ebel, RainerMilne, Bruce F.Deng, HaiGram, LoneJaspars, MarcelTabudravu, Jioji N.2023-02-122023-02-122017-05-040040-4020http://hdl.handle.net/10668/18888A new siderophore containing a 4,5-dihydroimidazole moiety was isolated from Pseudoalteromonas piscicida S2040 together with myxochelins A and B, alteramide A and its cycloaddition product, and bromo- and dibromoalterochromides. The structure of pseudochelin A was established by spectroscopic techniques including 2D NMR and MS/MS fragmentation data. In bioassays selected fractions of the crude extract of S2040 inhibited the opportunistic pathogen Pseudomonas aeruginosa. Pseudochelin A displayed siderophore activity in the chrome azurol S assay at concentrations higher than 50 mu M, and showed weak activity against the fungus Aspergillus fumigatus, but did not display antibacterial, anti-inflammatory or anticonvulsant activity. (C) 2017 Elsevier Ltd. All rights reserved.enAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/PseudoalteromonasSiderophorePseudochelin ANMRLCMSMicrobial iron transportCoordination chemistryPseudomonas-aeruginosaVibrio-choleraeMycobacterium-tuberculosisSiderocalinRecognitionAcquisitionPyochelinMicroorganismsresearch articleopen access10.1016/j.tet.2017.03.051https://backend.orbit.dtu.dk/ws/files/151633940/Pseudochelin_A_a_siderophore_of_Pseudoalteromonas_piscicida_S2040.pdf400226000007