Jose Caston, JuanDe la Torre, AlvaroRuiz-Camps, IsabelLuisa Sorli, MariaTorres, VicenteTorre-Cisneros, Julian2023-02-122023-02-122016-12-08Castón JJ, De la Torre Á, Ruiz-Camps I, Sorlí ML, Torres V, Torre-Cisneros J. Salvage Therapy with Ceftolozane-Tazobactam for Multidrug-Resistant Pseudomonas aeruginosa Infections. Antimicrob Agents Chemother. 2017 Feb 23;61(3):e02136-160066-4804http://hdl.handle.net/10668/19011Infections caused by multidrug-resistant Pseudomonas aeruginosa (MDRPA) present a major problem for therapeutic management. We report here our experience with 12 patients with a severe MDRPA infection (6 of which were pneumonia) who received salvage therapy with ceftolozane-tazobactam after inappropriate empirical treatment and/or suboptimal targeted treatment. Although 10 of the 12 patients (83.3%) experienced septic shock, only 3 patients (25%) died during the follow-up period. Microbiological cure in 7 patients (58.3%) was observed.enPseudomonas aeruginosaSalvage therapyCeftolozane-tazobactamUrinary-tract-infectionsDouble-blindCeftolozane/tazobactamresearch articleopen accessInfecciones urinariasTazobactam10.1128/AAC.02136-161098-6596https://europepmc.org/articles/pmc5328537?pdf=render394605900006