Cervera-Martínez, JoseAtienza-Carbonell, BeatrizMota, Jurema CBobes-Bascarán, TeresaCrespo-Facorro, BenedictoEsteban, CristinaGarcía-Portilla, María PazGomes-da-Costa, SusanaGonzález-Pinto, AnaJaén-Moreno, M JoséSarramea, FernandoVieta, EduardZorrilla, IñakiTabarés-Seisdedos, RafaelKapczinski, FlavioDe Boni, Raquel BBalanzá-Martínez, Vicent2025-01-072025-01-072021-08-24https://hdl.handle.net/10668/24546This study aimed to compare self-reported changes on lifestyle behaviors during two phases of the COVID-19 pandemic in Spain, and to evaluate clinical and sociodemographic factors associated with lifestyles. Two cross-sectional web surveys were conducted during lockdown (April 15-May 15, 2020) and seven months later (November 16-December 16, 2020). Lifestyle behaviors were self-reported by a multidimensional scale (SMILE-C). Two separate samples of respondents were analyzed. A multivariate regression model was performed to evaluate the association of SMILE-C scores with demographic and clinical variables. The sample comprised, 3412 participants from the first survey (S1) and in the S1 and 3635 from the second (S2). SMILE-C score decreased across surveys (p  The cross-sectional design and recruitment by non-probabilistic methods limit inferring causality and the external validity of the results. Overall lifestyle worsened seven months after the lockdown in Spain. Several demographic and clinical factors were associated with lifestyle scores. The contribution of common mental disorders to unhealthier lifestyles should be considered in order to prevent the negative impact of the pandemic.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/COVID-19General populationLifestyleMental healthWeb surveyAnxietyCOVID-19Communicable Disease ControlCross-Sectional StudiesDepressionHumansLife StyleMental HealthPandemicsSARS-CoV-2Surveys and Questionnairesresearch article34469856open access10.1016/j.jad.2021.08.0201573-2517PMC8418875https://doi.org/10.1016/j.jad.2021.08.020https://pmc.ncbi.nlm.nih.gov/articles/PMC8418875/pdf