Jiménez-Navarro, Manuel FMuñoz-García, AntonioRamírez-Marrero, Miguel ADomínguez-Franco, AntonioGarcía Alcántara, ÁngelGómez-Doblas, Juan JoséAlonso-Briales, JuanHernández-García, José MaríaSalva, DoloresRodríguez-Losada, Nde Teresa, Eduardo2014-10-032014-10-032009-09Jiménez-Navarro MF, Muñoz-García A, Ramírez-Marrero MA, Domínguez-Franco A, García Alcántara A, Gómez-Doblas JJ, et al. Preinfarction angina prior to first myocardial infarction does not influence long-term prognosis: a retrospective study with subgroup analysis in elderly and diabetic patients. Clin Cardiol. 2009 ; 32(9):E62-50160-9289http://hdl.handle.net/10668/1740Journal Article;BACKGROUND AND HYPOTHESIS Although prodromal angina occurring shortly before an acute myocardial infarction (MI) has protective effects against in-hospital complications, this effect has not been well documented after initial hospitalization, especially in older or diabetic patients. We examined whether angina 1 week before a first MI provides protection in these patients. METHODS A total of 290 consecutive patients, 143 elderly (>64 years of age) and 147 adults (<65 years of age), 68 of whom were diabetic (23.4%) and 222 nondiabetic (76.6%), were examined to assess the effect of preceding angina on long-term prognosis (56 months) after initial hospitalization for a first MI. RESULTS No significant differences were found in long-term complications after initial hospitalization in these adult and elderly patients according to whether or not they had prodromal angina (44.4% with angina vs 45.4% without in adults; 45.5% vs 58% in elderly, P < 0.2). Nor were differences found according to their diabetic status (61.5% with angina vs 72.7% without in diabetics; 37.3% vs 38.3% in nondiabetics; P = 0.4). CONCLUSION The occurrence of angina 1 week before a first MI does not confer long-term protection against cardiovascular complications after initial hospitalization in adult or elderly patients, whether or not they have diabetes.enAngina de pechoAncianoAngina inestableInsuficiencia cardíacaComplicaciones de la diabetesHospitalizaciónHumanosInfarto del miocardioReadmisión del pacienteModelos de riesgos proporcionalesRecurrenciaEstudios retrospectivosMedición de riesgoFactores de riesgoTerapia trombolíticaFactores de tiempoResultado del tratamientoMedical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia::Angina PectorisMedical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes ComplicationsMedical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Heart FailureMedical Subject Headings::Health Care::Health Care Facilities, Manpower, and Services::Health Services::Patient Care::HospitalizationMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle AgedMedical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia::Myocardial InfarctionMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Patient Care::Hospitalization::Patient ReadmissionMedical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Statistics as Topic::Models, Statistical::Proportional Hazards ModelsMedical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::RecurrenceMedical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies::Retrospective StudiesMedical Subject Headings::Health Care::Health Services Administration::Organization and Administration::Risk Management::Risk AssessmentMedical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Causality::Risk FactorsMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Thrombolytic TherapyMedical Subject Headings::Phenomena and Processes::Physical Phenomena::Time::Time FactorsMedical Subject Headings::Health Care::Health Services Administration::Quality of Health Care::Outcome and Process Assessment (Health Care)::Outcome Assessment (Health Care)::Treatment OutcomeMedical Subject Headings::Named Groups::Persons::Age Groups::Adult::AgedMedical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia::Angina Pectoris::Angina, Unstableresearch article19645043open access10.1002/clc.205131932-8737