Del Pozo, Maria Del PilarLope, VirginiaCriado-Navarro, InmaculadaPastor-Barriuso, RobertoFernandez de Larrea, NereaRuiz, EmmaCastello, AdelaLucas, PilarSierra, AngelesRomieu, IsabelleChajes, VeroniquePriego-Capote, FelicianoPerez-Gomez, BeatrizPollan, Marina2023-02-092023-02-092020-06-23Del Pozo MDP, Lope V, Criado-Navarro I, Pastor-Barriuso R, Fernández de Larrea N, et al. Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women. Nutrients. 2020 Jun 25;12(6):1895.http://hdl.handle.net/10668/15883This study investigates the still uncertain association between serum phospholipid fatty acids (PL-FA), and anthropometric and adiposity variables. A cross-sectional study was conducted with 1443 Spanish premenopausal women. Participants answered an epidemiological and a food frequency questionnaire. Anthropometric variables were measured using a bioimpedance scale. Serum PL-FAs levels were determined by gas chromatography-mass spectrometry. The association between body mass index (BMI), weight gain, body fat percentage, visceral fat index, and waist circumference with serum PL-FAs and desaturation indices was evaluated using multivariable linear regression models. BMI was positively associated with the relative concentration of saturated fatty acids (SFAs) (β = 0.94, q-val = 0.001), and with palmitoleic, dihomo-γ-linolenic (DGLA), arachidonic (AA) and α-linolenic acids, and was inversely associated with oleic, gondoic, trans-vaccenic, linoleic and γ-linolenic acids. Total fat percentage was positively associated with DGLA and AA, and inversely with linoleic and γ-linolenic acids. Low relative concentrations of some SFAs and high levels of n-6 PUFAs were associated with greater waist circumference. While the oleic/stearic and AA/DGLA acid ratios were inversely associated with BMI, DGLA/linoleic acid ratio was positively related to almost all variables. In addition to BMI, total fat percentage and waist circumference were also associated with certain individual fatty acids.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/body mass indexdesaturation indexfatfatty acidsobesityAdiposityAdultAnthropometryBody CompositionBody Mass IndexCross-Sectional StudiesFatty AcidsFatty Acids, Omega-6FemaleHumansMiddle AgedObesityPhospholipidsPremenopauseSpainWaist Circumferenceresearch article32630591open accessAdiposidadAdultoAntropometríaCircunferencia de la cinturaComposición corporalEspañaObesidadFosfolípidosPremenopausiaÁcidos grasosÁcidos grasos Omega-6Índice de masa corporal10.3390/nu120618952072-6643PMC7353394https://www.mdpi.com/2072-6643/12/6/1895/pdf?version=1593431359https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353394/pdf