Bouharras-El Idrissi, HichamMolina-Lopez, JorgeHerrera-Quintana, LourdesDominguez-Garcia, AlvaroLobo-Tamer, GabrielaPerez-Moreno, IrenePerez-de la Cruz, AntonioPlanells-del Pozo, Elena2023-02-122023-02-122016-11-010212-1611http://hdl.handle.net/10668/19459Introduction: Critically ill patients typically develop a catabolic stress state as a result of a systemic inflammatory response (SIRS) that alters clinical-nutritional biomarkers, increasing energy demands and nutritional requirements.Objective: To evaluate the status of albumin, prealbumin and transferrin in critically ill patients and the association between these clinical-nutritional parameters with the severity during a seven day stay in intensive care unit (ICU).Method: Multicenter, prospective, observational and analytical follow-up study. A total of 115 subjects in critical condition were included in this study. Clinical and nutritional parameters and severity were monitored at admission and at the seventh day of the ICU stay.Results: A significant decrease in APACHE II and SOFA (penAttribution-NonCommercial-ShareAlike 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-sa/4.0/Critically illSIRSAPACHEProtein metabolismPrealbuminTransferrinFast hugMalnutritionGuidelinesSupportresearch articleopen access10.20960/nh.7711699-5198https://doi.org/10.20960/nh.771432306700004