Relationship between nutritional treatment compliance and nutritional status improvements in patients with gastrointestinal impairment taking an oral peptide-based supplement.

López-Medina, José ALópez-Rodriguez, CristóbalEstornell-Gualde, María ARey-Fernández, LauraGómez-Senent, SilviaJoaquín-Ortiz, ClaraFernández-Soto, M LuisaHurtado-García, RobertoMartín-Martín, MargaritaBarrera-Martín, AnaVitales-Farrero, M TeresaMartínez-Ortega, Antonio JBlanca-Martínez-Barbeito, MaríaVázquez-Vizcaíno, BegoñaTasende-Fernández, ClaraPenacho-Lázaro, M ÁngelesJordá-Sorolla, EstherSánchez-Sánchez, RebecaDíaz-Gómez, LauraBaos-Fernández, SergioGuzmán-Rolo, GermánBallesteros-Pomar, María D2023-05-032023-05-032022-05-21http://hdl.handle.net/10668/22456Compliance in outpatients with gastrointestinal (GI) malabsorption is key in nutritional treatment. The objective of this study was to assess compliance in patients with GI impairment and malnutrition taking a high-calorie, high-protein, peptide-based oral nutritional supplement (ONS-PBD). A prospective, multicenter, observational study was conducted in 19 medical sites in Spain where ONS-PBD were prescribed as standard of care. Patients consumed ONS-PBD daily for 12 wk. Compliance was calculated as the percentage consumed of the prescribed amount of ONS per day. A total of 90 adult patients were included in the study, of whom 64 completed the 12-wk regimine. Mean compliance was 78.8% ± 24.5%. Risk of malnutrition decreased in 56.3% of patients at 12 wk, as measured with the malnutrition universal screening tool. A reduction in abdominal pain was observed and stool consistency improved, with a mean of 54.7% and 27.5%, respectively. Improvements in quality of life and a decrease in percentage of patients with severe functional impairment were observed. These data show that ONS-PBD compliance in malnourished patients with GI symptoms is high, reducing GI symptoms and improving patients' nutritional status.enAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/ComplianceEnteral formulasEnteral nutritionGastroenterologyGastrointestinal diseasesNutritionPeptide-based formulasAdultDietary SupplementsHumansMalnutritionNutritional StatusPatient CompliancePeptidesProspective StudiesQuality of LifeRelationship between nutritional treatment compliance and nutritional status improvements in patients with gastrointestinal impairment taking an oral peptide-based supplement.research article35839658open access10.1016/j.nut.2022.1117341873-1244https://doi.org/10.1016/j.nut.2022.111734