Cobo, FernandoRodríguez-Granger, JavierGómez-Camarasa, CristinaSampedro, AntonioAliaga-Martínez, LuisNavarro, José MaríaFernández, José Gutiérrez2016-10-052016-10-052016-09Cobo F, Rodríguez-Granger J, Gómez-Camarasa C, Sampedro A, Aliaga-Martínez L, Navarro JM, et al. Localized mucosal leishmaniasis caused by Leishmania infantum mimicking cancer in the rhinolaryngeal region. Int J Infect Dis.. 2016; 50:54-1201-9712http://hdl.handle.net/10668/2447Journal Article;The clinical, microbiological, and histopathological findings of six patients with mucosal leishmaniasis are reported. Five of these patients were Spanish with no history of travel abroad, while the other was from Bolivia but had lived in Spain for more than 5 years. Two patients had no underlying disease, while the other four had several other medical conditions. Lesions were located in the nose in three patients and in the larynx in the other three. Symptoms included difficulty in swallowing, nasal obstruction, dysphonia, and polypoid lesions mimicking cancer. The diagnosis was based on the identification of parasites, or on PCR assay or culture. Five patients were treated with liposomal amphotericin B and the other with antimonial compounds.enLeishmania infantumMucosal leishmaniasisGiemsaCultureCancerLeishmaniasis mucocutáneaReacción en cadena de la polimerasaParásitosAnfotericina BMegluminaMedical Subject Headings::Diseases::Parasitic Diseases::Protozoan Infections::Euglenozoa Infections::Leishmaniasis::Leishmaniasis, Cutaneous::Leishmaniasis, MucocutaneousMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain ReactionMedical Subject Headings::Organisms::Eukaryota::Animals::Invertebrates::ParasitesMedical Subject Headings::Chemicals and Drugs::Organic Chemicals::Lactones::Macrolides::Amphotericin BMedical Subject Headings::Chemicals and Drugs::Organic Chemicals::Alcohols::Sugar Alcohols::Sorbitol::MeglumineMedical Subject Headings::Diseases::Otorhinolaryngologic Diseases::Laryngeal Diseases::Voice Disorders::Hoarsenessresearch article27515498open access10.1016/j.ijid.2016.08.0031878-3511