Hmadcha, AbdelkrimAguilera, YolandaLozano-Arana, Maria DoloresMellado, NuriaSánchez, JavierMoya, CristinaSánchez-Palazón, LuisPalacios, JoseAntiñolo, GuillermoSoria, Bernat2016-07-042016-07-042016-05Hmadcha A, Aguilera Y, Lozano-Arana MD, Mellado N, Sánchez J, Moya C, et al. Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder. Stem Cell Res. 2016;16(3):635-91873-5061http://hdl.handle.net/10668/2247Lab resourceFrom 106 human blastocyts donate for research after in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD) for monogenetic disorder, 3 human embryonic stem cells (hESCs) HVR1, HVR2 and HVR3 were successfully derived. HVR1 was assumed to be genetically normal, HVR2 carrying Becker muscular dystrophy and HVR3 Hemophilia B. Despite the translocation t(9;15)(q34.3;q14) detected in HVR2, all the 3 cell lines were characterised in vitro and in vivo as normal hESCs lines and were registered in the Spanish Stem Cell Bank.spaCélulas madre embrionariasFertilización in VitroInvestigación básicaInvestigaciones con embrionesMedical Subject Headings::Anatomy::Cells::Stem Cells::Embryonic Stem Cells::Human Embryonic Stem CellsMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Reproductive Techniques::Reproductive Techniques, Assisted::Fertilization in VitroMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Obstetrical and Gynecological::Preimplantation DiagnosisMedical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell LineMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Embryo ResearchDerivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder.research article27346196open access10.1016/j.scr.2016.03.0121876-7753