Garcia-Rodriguez, Cruz EOlza, JosuneMesa, Maria DAguilera, Concepcion MMiles, Elizabeth ANoakes, Paul SVlachava, MariaKremmyda, Lefkothea-StellaDiaper, Norma DGodfrey, Keith MCalder, Philip CGil, Angel2023-01-252023-01-252016-06-08Garcia-Rodriguez CE, Olza J, Mesa MD, Aguilera CM, Miles EA, Noakes PS, et al. Fatty acid status and antioxidant defense system in mothers and their newborns after salmon intake during late pregnancy. Nutrition. 2017 Jan;33:157-162.http://hdl.handle.net/10668/10344The aim of the present study was to assess the maternal and newborn status of erythrocyte fatty acids and the antioxidant defense system after the intake of two portions of salmon per week during late pregnancy. Pregnant women (N = 123) were randomly assigned to continue their habitual diet, which was low in oily fish (control group, n = 61) or to consume two 150-g salmon portions per week (salmon group, n = 62) beginning at 20 wk of gestation and lasting until delivery. Fatty acids, selenium, and glutathione concentrations and antioxidant defense enzyme activities were measured in maternal erythrocytes at 20, 34, and 38 wk of pregnancy, and in cord erythrocytes collected at birth. Plasma concentrations of antioxidant molecules were measured. Compared with the control group, consuming salmon had little effect on erythrocyte fatty acids in either mothers or newborns. Components of the antioxidant defense system did not differ between groups. Glutathione peroxidase activity and the concentrations of tocopherols, retinol, and coenzyme Q10 were significantly lower in cord blood compared with maternal blood at week 38 in both groups. Maternal and newborn erythrocyte fatty acids are not strongly affected by the intake of two portions of salmon per week during the second half of pregnancy, although erythrocyte docosahexaenoic acid might be increased in newborns. Maternal and newborn antioxidant defense systems are not impaired by intake of salmon from 20 wk gestation.enAntioxidantsFatty acidsFish oilsNewbornPregnancyω-3AdultAnimalsAntioxidantsEnglandErythrocytesFatty AcidsFemaleFetal BloodGlutathioneGlutathione PeroxidaseHumansInfant, NewbornMaleMaternal Nutritional Physiological PhenomenaNutritional StatusOxidative StressPregnancyPregnancy Trimester, SecondPregnancy Trimester, ThirdSalmonSeafoodSeleniumresearch article27497519Restricted AccessAlimentos marinosAdultoAnimalesAntioxidantesEmbarazoEritrocitosEstado nutricionalEstrés oxidativoFemeninoFenómenos fisiologicos nutricionales maternosGlutatiónRecién nacidoSalmón10.1016/j.nut.2016.05.0151873-1244https://eprints.soton.ac.uk/399304/2/Prof%2520Calder_Accepted%2520publications%2520for%2520eprints_15_NUT-D-16-00035R2.pdf