Bikdeli, BehnoodLobo, José LuisJiménez, DavidGreen, PhilipFernández-Capitán, CarmenBura-Riviere, AlessandraOtero, RemediosDiTullio, Marco RGalindo, SilviaEllis, MartinParikh, Sahil AMonreal, ManuelRIETE Investigators2023-01-252023-01-252018http://hdl.handle.net/10668/13139Background Transthoracic echocardiography ( TTE ) is often considered for risk stratification of patients with acute pulmonary embolism ( PE ). We sought to determine the contemporary utilization of early TTE (within 72 hours of PE diagnosis) and explored the association between TTE findings and PE -related mortality. Methods and Results Data from the RIETE (Registro Informatizado Enfermedad TromboEmbolica) registry, a multicenter registry of consecutive patients with acute PE , were used (2001-July 2017). We used a generalized linear mixed model to determine predictors of early TTE performance. Moreover, the association between 3 TTE variables (right atrial enlargement, right ventricular hypokinesis, and presence of right heart thrombi) and 30-day PE -related mortality was assessed in generalized linear mixed models adjusted for PE severity index, and other comorbidities. Among 35 935 enrollees with acute PE , 15 375 (42.8%) underwent early TTE . There was an increase in early TTE utilization rate over time ( PenAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/echocardiographypulmonary embolismtrendsAcute DiseaseAge FactorsAgedAged, 80 and overAtrial FibrillationCoronary DiseaseEchocardiographyFemaleHeart AtriaHeart DiseasesHeart FailureHumansHypotensionLinear ModelsMaleMiddle AgedPulmonary EmbolismRisk AssessmentSex FactorsTachycardiaThrombosisVentricular Dysfunction, Rightresearch article30371152open access10.1161/JAHA.118.0090422047-9980PMC6201438https://doi.org/10.1161/jaha.118.009042https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201438/pdf