Fagundo-Rivera, JavierAllande-Cussó, ReginaOrtega-Moreno, MónicaGarcía-Iglesias, Juan JesúsRomero, AdolfoRuiz-Frutos, CarlosGómez-Salgado, Juan2023-01-202023-01-202021-05-30Fagundo-Rivera J, Allande-Cussó R, Ortega-Moreno M, García-Iglesias JJ, Romero A, Ruiz-Frutos C, et al. Implications of Lifestyle and Occupational Factors on the Risk of Breast Cancer in Shiftwork Nurses. Healthcare. 2021 May 30;9(6):649http://hdl.handle.net/10668/4602Shift work that involves circadian disruption has been highlighted as a likely carcinogenic factor for breast cancer in humans. Also, unhealthy lifestyle habits observed in night work nurses could be causally related to an increase in the incidence of estrogen-positive breast tumours in this population. Assessing baseline risk of breast cancer in nurses is essential. The objective of this study was to analyze the risk of breast cancer that nurses had in relation to their lifestyle and labour factors related to shift work. A cross-sectional descriptive study through a questionnaire about sociodemographic variables, self-perception of health, and working life was designed. The sample consisted of 966 nurses. The relationship between variables was tested. A binary logistic regression and a classification and regression tree were performed. The most significant labour variables in relation to the risk of breast cancer were the number of years worked (more than 16 years; p < 0.01; OR = 8.733, 95% CI = 2.811, 27.134) and the total years performing more than 3 nights per month (10 or more years; p < 0.05; OR = 2.294, 95% CI = 1.008, 5.220). Also, the nights worked throughout life (over 500; OR = 4.190, 95% CI = 2.118, 8.287) were significant in the analysis. Nurses who had or ever had breast cancer valued their self-perceived health more negatively (p < 0.001) and referred a lower quality of sleep (p < 0.001) than the non-cases nurses. The occupational factors derived from night work could have several impacts on nurses' health and their family-work balance. Promoting healthy lifestyles, informing about shift work risks, and adjusting shift work schedules are critical methods to decrease the possible effects of circadian disruption in nurses.enAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/Breast cancerNight workShift workHealth personnelOccupational diseaseWorking conditionsPreventionCarcinogensNeoplasias de la mamaHorario de trabajo por turnosPersonal de saludEnfermedades profesionalesCondiciones de trabajoPrevención de enfermedadesCarcinógenosEnfermerasEquilibrio entre vida personal y laboralTrastornos cronobiológicosMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Breast Diseases::Breast NeoplasmsMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional StudiesMedical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Noxae::CarcinogensMedical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Mammary Neoplasms, AnimalMedical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Life StyleMedical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::EstrogensMedical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Life StyleMedical Subject Headings::Persons::Persons::Occupational Groups::Health PersonnelMedical Subject Headings::Check Tags::FemaleMedical Subject Headings::Persons::Persons::Occupational Groups::Health Personnel::NursesMedical Subject Headings::Diseases::Nervous System Diseases::Chronobiology Disordersresearch article34070908Acceso abierto10.3390/healthcare90606492227-9032PMC8228409