Uribarri, AitorNúñez-Gil, Iván JAparisi, AlvaroBecerra-Muñoz, Victor MFeltes, GiselaTrabattoni, DanielaFernández-Rozas, InmaculadaViana-Llamas, María CPepe, MartinoCerrato, EnricoCapel-Astrua, ThamarRomero, RodolfoCastro-Mejía, Alex FEl-Battrawy, IbrahimLópez-País, JavierD'Ascenzo, FabrizioFabregat-Andres, OscarBardají, AlfredoRaposeiras-Roubin, SergioMarín, FranciscoFernández-Ortiz, AntonioMacaya, CarlosEstrada, VicenteHOPE COVID-19 Investigators2023-02-092023-02-092020-06-29http://hdl.handle.net/10668/15851Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite its international aggressive extension, with a significant morbidity and mortality, the impact of renal function on its prognosis is uncertain. Analysis from the international HOPE-Registry (NCT04334291). The objective was to evaluate the association between kidney failure severity on admission with the mortality of patients with SARS-CoV-2 infection. Patients were categorized in 3 groups according to the estimated glomerular filtration rate on admission (eGFR > 60 mL/min/1.73 m2, eGFR 30-60 mL/min/1.73 m2 and eGFR  60 mL/min/1.73 m2, eGFR 30-60 mL/min/1.73 m2 and eGFR  758 patients were included: mean age was 66 ± 18 years, and 58.6% of patient were male. Only 8.5% of patients had a history of chronic kidney disease (CKD); however, 30% of patients had kidney dysfunction upon admission (eGFR  60 vs eGFR 30-60 vs and eGFR  Renal failure on admission in patients with SARS-CoV-2 infection is frequent and is associated with a greater number of complications and in-hospital mortality. Our data comes from a multicenter registry and therefore does not allow to have a precise mortality risk assessment. More studies are needed to confirm these findings.enAcute kidney injuryCOVID-19Chronic kidney failureMortalityPrognosisRegistryAcute Kidney InjuryAgedAged, 80 and overAngiotensin-Converting Enzyme 2BetacoronavirusCOVID-19Coronavirus InfectionsFemaleGlomerular Filtration RateHumansMaleMiddle AgedPandemicsPeptidyl-Dipeptidase APneumonia, ViralRegistriesRisk AssessmentSARS-CoV-2research article32602006open access10.1007/s40620-020-00790-51724-6059PMC7322375https://link.springer.com/content/pdf/10.1007/s40620-020-00790-5.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322375/pdf