Salinas-Asensio, Maria Del MarOcon-Hernandez, OlgaMundo-Lopez, AntonioFernandez-Lao, CarolinaPeinado, Francisco MPadilla-Vinuesa, CarmenAlvarez-Salvago, FranciscoPostigo-Martin, PaulaLozano-Lozano, MarioLara-Ramos, AnaArroyo-Morales, ManuelCantarero-Villanueva, IreneArtacho-Cordon, Francisco2023-05-032023-05-032022-01-30Salinas-Asensio MDM, Ocón-Hernández O, Mundo-López A, Fernández-Lao C, Peinado FM, Padilla-Vinuesa C, et al. 'Physio-EndEA' Study: A Randomized, Parallel-Group Controlled Trial to Evaluate the Effect of a Supervised and Adapted Therapeutic Exercise Program to Improve Quality of Life in Symptomatic Women Diagnosed with Endometriosis. Int J Environ Res Public Health. 2022 Feb 2;19(3):1738.http://hdl.handle.net/10668/21025The 'Physio-EndEA' study aims to explore the potential benefits of a therapeutic exercise program (focused on lumbopelvic stabilization and tolerance to exertion) on the health-related quality of life (HRQoL) of symptomatic endometriosis women. The present study will use a parallel-group randomized controlled trial design. A total of 22 symptomatic endometriosis women will be randomized 1:1 to the Physio-EndEA or usual care groups. The 'Physio-EndEA' program will consist of a one-week lumbopelvic stabilization learning phase followed by an eight-week phase of stretching, aerobic and resistance exercises focused on the lumbopelvic area that will be sequentially instructed and supervised by a trained physiotherapist (with volume and intensity progression) and adapted daily to the potential of each participant. The primary outcome measure is HRQoL. The secondary outcome measures included clinician-reported outcomes (pressure pain thresholds, muscle thickness and strength, flexibility, body balance and cardiorespiratory fitness) and patient-reported outcomes (pain intensity, physical fitness, chronic fatigue, sexual function, gastrointestinal function and sleep quality). Findings of this study will help to identify cost-effective non-pharmacological options (such as this exercise-based intervention) that may contribute to the improvement of HRQoL in symptomatic endometriosis women.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/endometriosismotor controlpainphysiotherapyquality of lifetherapeutic exerciseEndometriosisExerciseExercise TherapyFemaleHumansPhysical FitnessQuality of LifeTreatment Outcomeresearch article35162761open accessAptitud físicaCalidad de vidaEjercicio físicoEndometriosisFemeninoHumanosResultado del tratamientoTerapia por ejercicio10.3390/ijerph190317381660-4601PMC8834829https://www.mdpi.com/1660-4601/19/3/1738/pdf?version=1644385240https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834829/pdf