Gómez-Perez, Ana MaríaDamas-Fuentes, MiguelCornejo-Pareja, IsabelTinahones, Francisco J.2022-12-052022-12-052021-09-29Gómez-Perez AM, Damas-Fuentes M, Cornejo-Pareja I, Tinahones FJ. Heart Failure in Type 1 Diabetes: A Complication of Concern? A Narrative Review. J Clin Med. 2021 Sep 29;10(19):4497http://hdl.handle.net/10668/4458Heart failure (HF) has been a hot topic in diabetology in the last few years, mainly due to the central role of sodium-glucose cotransporter 2 inhibitors (iSGLT2) in the prevention and treatment of cardiovascular disease and heart failure. It is well known that HF is a common complication in diabetes. However, most of the knowledge about it and the evidence of cardiovascular safety trials with antidiabetic drugs refer to type 2 diabetes (T2D). The epidemiology, etiology, and pathophysiology of HF in type 1 diabetes (T1D) is still not well studied, though there are emerging data about it since life expectancy for T1D has increased in the last decades and there are more elderly patients with T1D. The association of T1D and HF confers a worse prognosis than in T2D, thus it is important to investigate the characteristics, risk factors, and pathophysiology of this disease in order to effectively design prevention strategies and therapeutic tools.enAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/Type 1 diabetesHeart failureCardiovascular diseaseDiabetic myocardiopathyDiabetes Mellitus tipo 1Insuficiencia cardíacaEnfermedades cardiovascularesCardiomiopatíasComplicaciones de la diabetesMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Persons::Persons::Age Groups::Adult::AgedMedical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 1Medical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 2Medical Subject Headings::Diseases::Cardiovascular DiseasesMedical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hypoglycemic AgentsMedical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Heart FailureMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk FactorsMedical Subject Headings::Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::GlucoseMedical Subject Headings::Health Care::Population Characteristics::Demography::Vital Statistics::Life ExpectancyMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosisreview article34640518open access10.3390/jcm101944972077-0383PMC8509458