Calado, Sofia MGarcia-Delgado, Ana BDe la Cerda, BertaPonte-Zuñiga, BeatrizBhattacharya, Shom SDíaz-Corrales, Francisco J2023-01-252023-01-252018-11-16http://hdl.handle.net/10668/13226Retinitis pigmentosa (RP) is an inherited retinal degenerative disease. Mutations in EYS have been associated with autosomal recessive RP. The human iPS cell line, CABi002-A, derived from peripheral blood mononuclear cells from a patient carrying a heterozygous double mutation in EYS gene was generated by non-integrative reprogramming technology, using hOCT3/4, hSOX2, hc-MYC and hKLF4 reprogramming factors. Pluripotency and differentiation capacity were assessed by immunocytochemistry and RT-PCR. This iPSC line can be further differentiated towards the affected cells to understand the pathophysiology of the disease and test new therapeutic strategies.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/AdultEye ProteinsHumansInduced Pluripotent Stem CellsMaleMutationRetinitis Pigmentosaresearch article30471616open access10.1016/j.scr.2018.11.0021876-7753https://doi.org/10.1016/j.scr.2018.11.002