Merchan-Ramirez, ElisaSanchez-Delgado, GuillermoArrizabalaga-Arriazu, CristinaAcosta, Francisco MArias-Tellez, Maria JoseMuñoz-Torres, ManuelGarcia-Lario, Jose VLlamas-Elvira, Jose MRuiz, Jonatan R2023-05-032023-05-032022-04-06Merchan-Ramirez E, Sanchez-Delgado G, Arrizabalaga-Arriazu C, Acosta FM, Arias-Tellez MJ, Muñoz-Torres M, et al. Circulating concentrations of free triiodothyronine are associated with central adiposity and cardiometabolic risk factors in young euthyroid adults. J Physiol Biochem. 2022 Aug;78(3):629-640.http://hdl.handle.net/10668/21330Thyroid dysfunction is associated with classic cardiometabolic risk factors in humans. However, this relationship remains unclear in young euthyroid adults. The present work examines the associations of circulating thyroid hormones (THs) and thyroid-stimulating hormone (TSH) concentrations with body composition and cardiometabolic risk factors in young euthyroid adults. A total of 106 sedentary, euthyroid adults (72 women; 22 ± 2 years old) participated in this cross-sectional study. THs and TSH serum concentrations were determined in fasting conditions (6 h). Body composition (fat mass (FM), lean mass (LM), and visceral adipose tissue (VAT)) was determined by dual-energy X-ray absorptiometry, anthropometric parameters (weight, height, and waist circumference) were measured, and neck adipose tissue mass was quantified through computed tomography (CT) scanning. Cardiometabolic risk factors including fasting glucose and lipid metabolism markers, hepatic phosphatase and transaminases, and blood pressure were also assessed. Free triiodothyronine (FT3) concentration was positively associated with body mass index, LM, VAT, and waist circumference (all P ≤ 0.038). FT3 was also associated with glucose, insulin, HOMA-IR, fatty liver index, and blood pressure (all P enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Body compositionCardiometabolic risk factorsEuthyroidObesityThyroid functionAdiposityBody Mass IndexCardiometabolic Risk FactorsCross-Sectional StudiesFatty LiverFemaleGlucoseHumansMaleObesityObesity, AbdominalRisk FactorsThyroid HormonesThyrotropinThyroxineTriiodothyronineYoung Adultresearch article35381950open accessAdiposidadCardiometabólicoFemeninoGlucosaHormonas tiroideasHumanosHígado grasoObesidadObesidad abdominalTirotropinaTiroxinaTriyodotironinaÍndice de masa corporal10.1007/s13105-022-00881-w1877-8755PMC9381449https://link.springer.com/content/pdf/10.1007/s13105-022-00881-w.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381449/pdf