Rodilla, EnriqueLópez-Carmona, Maria DoloresCortes, XaviCobos-Palacios, LidiaCanales, SergioSáez, Maria CarmenCampos Escudero, SamaraRubio-Rivas, ManuelDíez Manglano, JesusFreire Castro, Santiago JVázquez Piqueras, NuriaMateo Sanchis, ElisabethPesqueira Fontan, Paula MariaMagallanes Gamboa, Jeffrey OskarGonzález García, AndrésMadrid Romero, VictorTamargo Chamorro, LaraGonzález Moraleja, JulioVillanueva Martínez, JavierGonzález Noya, AmaraSuárez-Lombraña, AnaGracia Gutiérrez, AnyuliLópez Reboiro, Manuel LorenzoRamos Rincón, José ManuelGómez Huelgas, RicardoSEMI-COVID-19 Network2023-02-092023-02-092020-12-30http://hdl.handle.net/10668/16876Older age and cardiovascular comorbidities are well-known risk factors for all-cause mortality in patients with coronavirus disease 2019 (COVID-19). Hypertension and age are the 2 principal determinants of arterial stiffness (AS). This study aimed to estimate AS in patients with COVID-19 requiring hospitalization and analyze its association with all-cause in-hospital mortality. This observational, retrospective, multicenter cohort study analyzed 12 170 patients admitted to 150 Spanish centers included in the SEMI-COVID-19 Network. We compared AS, defined as pulse pressure ≥60 mm Hg, and clinical characteristics between survivors and nonsurvivors. Mean age was 67.5 (±16.1) years and 42.5% were women. Overall, 2606 (21.4%) subjects died. Admission systolic blood pressure (BP)enCOVID-19arterial stiffnessblood pressureheart failurehypertensionpulse pressureAge FactorsAgedAged, 80 and overBlood PressureCOVID-19Cardiovascular DiseasesCause of DeathComorbidityFemaleHospital MortalityHumansHypertensionKaplan-Meier EstimateMaleMiddle AgedObesityOdds RatioPandemicsPrognosisPulmonary Disease, Chronic ObstructiveRegistriesRetrospective StudiesSARS-CoV-2SpainVascular Stiffnessresearch article33377393open access10.1161/HYPERTENSIONAHA.120.165631524-4563PMC7884247https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.120.16563https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884247/pdf