Guillen-Ponce, CLastra, ELorenzo-Lorenzo, IMartin Gomez, TMorales Chamorro, RSanchez-Heras, A BSerrano, RSoriano Rodriguez, M CSoto, J LRobles, L2023-02-082023-02-082019-12-16Guillén-Ponce C, Lastra E, Lorenzo-Lorenzo I, Martín Gómez T, Morales Chamorro R, Sánchez-Heras AB, et al. SEOM clinical guideline on hereditary colorectal cancer (2019). Clin Transl Oncol. 2020 Feb;22(2):201-212http://hdl.handle.net/10668/15004In the last 2 decades, clinical genetics on hereditary colorectal syndromes has shifted from just a molecular characterization of the different syndromes to the estimation of the individual risk of cancer and appropriate risk reduction strategies. In the last years, new specific therapies for some subgroups of patients have emerged as very effective alternatives. At the same time, germline multigene panel testing by next-generation sequencing (NGS) technology has become the new gold standard for molecular genetics.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Adenomatous polyposisColon cancerHereditary colorectal cancerLynch syndromeClinical trials as topicColorectal neoplasmsGenetic predisposition to diseaseHumansMedical oncologyMutationNeoplasm proteinsPractice guidelines as topicSocieties, medicalresearch article31981079open accessMutaciónNeoplasias colorrectalesOncología médicaPredisposición genética a la enfermedadProteínas de neoplasiasSociedades médicas10.1007/s12094-019-02272-y1699-3055https://link.springer.com/content/pdf/10.1007/s12094-019-02272-y.pdf