Martín-Martín, LydiaMembrilla-Mesa, Miguel DavidLozano-Lozano, MarioGaliano-Castillo, NoeliaFernández-Lao, CarolinaArroyo-Morales, Manuel2023-01-252023-01-252019-07-242077-0383http://hdl.handle.net/10668/14306Patients often experience pain as a result of a stroke. However, the mechanism of this pain remains uncertain. Our aim was to investigate the relationship between pressure pain thresholds (PPTs) and disability pain in patients with hemiplegic shoulder pain (HSP). Methods: Twenty-six post-stroke patients (age 53.35 ± 13.09 years) and healthy controls (54.35 ± 12.37 years) participated. We investigated spontaneous shoulder pain, disability pain perception through the shoulder pain and disability index (SPADI), and the PPTs over joint C5-C6, upper trapezius, deltoid, epicondyle, second metacarpal, and tibialis anterior, bilaterally. The analysis of variance (ANOVA) showed significant differences in pain between groups (p Post-stroke patients showed a relationship between widespread pressure pain hypersensitivity with lower PPT levels and pain disability perception, suggesting a central sensitization mediated by bilateral and symmetric pain patterns.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/central sensitizationdisabilitypainpressure pain thresholdsstrokeresearch article31344928open access10.3390/jcm8081093PMC6722959https://www.mdpi.com/2077-0383/8/8/1093/pdf?version=1564132682https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722959/pdf