Pascual, IsaacMuñoz-García, Antonio JLópez-Otero, DiegoAvanzas, PabloJiménez-Navarro, Manuel FCid-Alvarez, BelénValle, Raquel delAlonso-Briales, Juan HOcaranza-Sánchez, RaimundoHernández, José MTrillo-Nouche, RamiroMorís, César2015-11-132015-11-132015-07-04Pascual I, Muñoz-García AJ, López-Otero D, Avanzas P, Jiménez-Navarro MF, Cid-Álvarez B, et al. Transcatheter aortic valve implantation in very elderly patients: immediate results and medium term follow-up. J Geriatr Cardiol. 2015; 12(4):340-5http://hdl.handle.net/10668/2052Journal Article;OBJECTIVE To evaluate immediate transcatheter aortic valve implantation (TAVI) results and medium-term follow-up in very elderly patients with severe and symptomatic aortic stenosis (AS). METHODS This multicenter, observational and prospective study was carried out in three hospitals. We included consecutive very elderly (> 85 years) patients with severe AS treated by TAVI. The primary endpoint was to evaluate death rates from any cause at two years. RESULTS The study included 160 consecutive patients with a mean age of 87 ± 2.1 years (range from 85 to 94 years) and a mean logistic EuroSCORE of 18.8% ± 11.2% with 57 (35.6%) patients scoring ≥ 20%. Procedural success rate was 97.5%, with 25 (15.6%) patients experiencing acute complications with major bleeding (the most frequent). Global mortality rate during hospitalization was 8.8% (n = 14) and 30-day mortality rate was 10% (n = 16). Median follow up period was 252.24 ± 232.17 days. During the follow-up period, 28 (17.5%) patients died (17 of them due to cardiac causes). The estimated two year overall and cardiac survival rates using the Kaplan-Meier method were 71% and 86.4%, respectively. Cox proportional hazard regression showed that the variable EuroSCORE ≥ 20 was the unique variable associated with overall mortality. CONCLUSIONS TAVI is safe and effective in a selected population of very elderly patients. Our findings support the adoption of this new procedure in this complex group of patients.enAortic stenosisHigh surgical riskTranscatheter aortic valveVery elderly patientsReemplazo de la válvula aórtica transcatéterHumanosAncianoEstenosis de la válvula aórticaTasa de supervivenciaHemorragiaMedical Subject Headings::Named Groups::Persons::Age Groups::Adult::AgedMedical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Heart Valve Diseases::Aortic Valve StenosisMedical Subject Headings::Health Care::Population Characteristics::Demography::Vital Statistics::Mortality::Survival RateMedical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::HemorrhageMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Prosthesis Implantation::Heart Valve Prosthesis ImplantationMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humansresearch article26345138open access10.11909/j.issn.1671-5411.2015.04.0051671-5411PMC4554786