Perez Lara, Francisco JavierHebrero Jimenez, Maria LuisaMoya Donoso, Francisco JavierHernandez Gonzalez, Jose ManuelMartinez, Maria PitarchArjona, Tatiana Prieto-Puga2025-01-072025-01-072021-09-151948-5204https://hdl.handle.net/10668/24555Colorectal cancer is one of the most prevalent tumours, but with improved treatment and early detection, its prognosis has greatly improved in recent years. However, when the tumour is locally advanced at diagnosis or if there is local recurrence, it is more difficult to perform a complete tumour resection, and there may be a residual macroscopic tumour. In this paper, we review the literature on residual macroscopic tumour resections, concerning both locally advanced primary tumours and recurrences, evaluating the main problems encountered, the treatments applied, the prognosis and future perspectives in this field.enAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/Rectal cancerSurgeryTreatmentIncomplete resectionLocal recurrencePostoperative radiation-therapyRecurrent colorectal-cancerPelvic exenterationSmall-bowelSurgical-managementMultimodality treatmentLocal recurrenceIntraoperative radiotherapyRadical resectionSurgeryreview34616512open access10.4251/wjgo.v13.i9.1062https://doi.org/10.4251/wjgo.v13.i9.1062736478800006