Rodriguez-Leor, OriolSegura, JuliánGarcía Donaire, José AntonioGutiérrez-Ibañes, EnriqueOliveras, AnnaMediavilla, Juan DiegoSerrador, AnaPrado, José CarlosNuñez-Gil, IvánDíez-Delhoyo, FelipeClarà Velasco, AlbertJaén Águila, FernandoAmat-Santos, IgnacioBayes-Genis, AntoniTroya Saborido, María Isabel2023-01-252023-01-252019-09-24http://hdl.handle.net/10668/14562Renal denervation is a percutaneous intervention for the treatment of resistant hypertension. Randomized studies have shown contradictory results on its efficacy. We present the results of a renal denervation registry for the treatment of resistant hypertension in real-life patients in Spain. Multicenter registry of consecutive patients with resistant hypertension treated with renal denervation in Spain between 2009 and 2018. We included 125 patients (mean age, 56 years; 41% female; mean onset of hypertension 14±9 years previously). Office systolic and diastolic blood pressure and ambulatory blood pressure monitoring decreased 6 months after the intervention (166±20/95±16 to 149±22/87±16 mmHg and 151±14/89±12 to 143±15/84±11, both P In patients with resistant hypertension, treatment with renal denervation was related to a decrease in office blood pressure and, more importantly, in ambulatory blood pressure monitoring, with a significant reduction in pharmacological treatment.enBlood pressureDenervación renal percutáneaHipertensión arterialHypertensionPercutaneous renal denervationPresión arterialSistema nervioso simpáticoSympathetic nervous systemAntihypertensive AgentsBlood PressureBlood Pressure Monitoring, AmbulatoryDenervationFemaleHumansHypertensionKidneyMaleMiddle AgedRegistriesSpainSympathectomyTreatment OutcomeRenal denervation for the treatment of resistant hypertension in Spain. The Flex-Spyral Registry.research article31561981open access10.1016/j.rec.2019.08.0011885-5857http://repositori.upf.edu/bitstream/10230/44494/1/rodriguez-rec-dene.pdf