Chacón López-Muñiz, J Ide la Cruz Merino, LGavilá Gregori, JMartínez Dueñas, EOliveira, MSeguí Palmer, M AÁlvarez López, IAntolin Novoa, SBellet Ezquerra, MLópez-Tarruella Cobo, S2023-01-252023-01-252019-01-08http://hdl.handle.net/10668/13387Although the metastasic breast cancer is still an incurable disease, recent advances have increased significantly the time to progression and the overall survival. However, too much information has been produced in the last 2 years, so a well-based guideline is a valuable document in treatment decision making. The SEOM guidelines are intended to make evidence-based recommendations on how to manage patients with advanced and recurrent breast cancer to achieve the best patient outcomes based on a rational use of the currently available therapies. To assign a level of certainty and a grade of recommendation the United States Preventive Services Task Force guidelines methodology was selected as reference.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/AdvancedBreast cancerGuidelinesLoco-regional recurrenceSEOMBreast NeoplasmsClinical Trials as TopicCombined Modality TherapyDisease ManagementFemaleHumansNeoplasm Recurrence, LocalPractice Guidelines as TopicPrognosisSocieties, Medicalresearch article30617924open access10.1007/s12094-018-02010-w1699-3055PMC6339670https://link.springer.com/content/pdf/10.1007/s12094-018-02010-w.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339670/pdf