Martínez-Sellés, ManuelDíez-Villanueva, PabloÁlvarez Garcia, JesúsFerrero-Gregori, AndreuVives-Borrás, MiquelWorner, FernandoBardají, AlfredoDelgado, Juan FVázquez, RafaelGonzález-Juanatey, José RFernández-Aviles, FranciscoCinca, Juan2023-01-252023-01-252018-07-23http://hdl.handle.net/10668/12485Female sex is an independent predictor of better survival in patients with heart failure (HF), but the mechanism of this association is unknown. On the other hand, pregnancies have a strong influence on the cardiovascular system. Sex and previous gestations might have a prognostic impact on 1-year mortality in patients admitted with HF. We conducted an observational, prospective, consecutive, multicenter registry of 1831 patients (756 females [41.2%]) admitted with HF. Females had a more advanced age (75.2 ±11.4 vs 70.4 ±12.2 years), less ischemic heart disease (167 [25.3%] vs 446 [47.3%]), and higher left ventricular ejection fraction (52.0% ±16.6% vs 41.1% ±17.0%) than did men (all P values In patients admitted with HF, female sex and the number of previous pregnancies are independently associated with better 1-year survival.enHeart FailurePregnancyPrognosisSexAgedFemaleFollow-Up StudiesHeart FailureHumansInpatientsMalePregnancyPrognosisProspective StudiesRegistriesRisk AssessmentRisk FactorsSex DistributionSex FactorsSpainSurvival Rateresearch article29774566open access10.1002/clc.229791932-8737PMC6489862https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/clc.22979https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489862/pdf