Coronado, Pluvio JRychlik, AgnieszkaBaquedano, LauraGarcía-Pineda, VirginiaMartínez-Maestre, Maria AQuerleu, DenisZapardiel, Ignacio2023-05-032023-05-032022-02-212072-6694http://hdl.handle.net/10668/20876(1) Background: This study aimed to analyze the impact of surgical approach on survival rates in women diagnosed with endometrial cancer. (2) Methods: A retrospective multicenter cohort of 1382 women diagnosed with EC was performed. A total of 684 (49.5%) women underwent minimally invasive surgery, 233 (34%) underwent robotic-assisted laparoscopy (RAL), 451 (66%) underwent conventional laparoscopy (LPS), and 698 (50.5%) underwent open surgery (OP). Sociodemographic features, tumor characteristics, and survival rates were analyzed in the whole sample and in a matched-pair model. (3) Results: Women operated on by OP were significantly older, presented more comorbidities, and had more aggressive tumors. Disease-free (DFS), overall (OS), and specific survival related to EC (SS) amounts were significantly higher for MIS compared to OP (penAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/endometrial carcinomalaparoscopylaparotomymorbidityopen approachrobotic-assisted laparoscopysurvivalresearch article35205829open access10.3390/cancers14041081PMC8870025https://www.mdpi.com/2072-6694/14/4/1081/pdf?version=1645436775https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870025/pdf