Rodríguez-Baño, Jesús2015-10-212015-10-212015-09Rodríguez-Baño J. The Times They Are a-Changin': Carbapenems for Extended-Spectrum-β-Lactamase-Producing Bacteria. Antimicrob Agents Chemother. 2015; 59(9):5095-60066-4804http://hdl.handle.net/10668/2029Journal Article;Several antimicrobial agents are being investigated as alternatives to carbapenems in the treatment of infections caused by ESBL-producing Enterobacteriaceae, which may be useful in avoiding overuse of carbapenems in the context of recent global spread of carbapenem-resistant Enterobacteriaceae. The most promising candidates for invasive infections so far are β-lactam/β-lactamase inhibitor combinations and cephamycins.enEnterobacteriaceaeInfecciones por enterobacteriaceaeInhibidores de betalactamasasLactamsCarbapenémicosCefamicinasBeta-lactamasMedical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::CarbapenemsMedical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::Cephalosporins::CephamycinsMedical Subject Headings::Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::EnterobacteriaceaeMedical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Enterobacteriaceae InfectionsMedical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::LactamsMedical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactamsresearch article26100709open access10.1128/AAC.01333-151098-6596PMC4538486