Cabeza, Juan FernandezAristizabal-Duque, Cristhian HSanchez, Isabel Maria BlancasOrtiz, Martin RuizAlmodovar, Ana RodriguezOrtega, Monica DelgadoMartinez, Fatima EstebanSaldaña, Manuel RomeroDel Pozo, Francisco Javier FonsecaAlvarez-Ossorio, Manuel PanRubio, Maria Dolores Mesa2023-05-032023-05-032022-01-17Cabeza JF, Aristizábal-Duque CH, Sánchez IMB, Ortiz MR, Almodóvar AR, Ortega MD, et al. Relationship between overweight and obesity and cardiac dimensions and function in a paediatric population. Eur J Pediatr. 2022 May;181(5):1943-1949http://hdl.handle.net/10668/20119Obesity in adults is associated with left ventricular hypertrophy, dilatation, and myocardial fibrosis, as well as heart failure and coronary heart disease. These associations have been studied to a lesser extent in the paediatric population. This study aims to investigate the relationship between obesity and cardiac structure and function in the paediatric population. In a southern Spanish village, we selected all inhabitants aged 6-17 years stratifying by age, gender, and educational centres. We performed a complete transthoracic echocardiogram evaluating all the cardiac morphological and functional parameters commonly measured in an echocardiographic study. There were 212 children and adolescents included. Of them, 48.1% were males. The mean age was 10.9 ± 3.0 years. A total of 106 (50%) were normal weight, 57 (26.9%) overweight, and 49 (23.1%) obese. Sex and age were similar in all three groups. Overweight and obesity were associated with larger left ventricular end-diastolic and end-systolic volumes (p  Childhood obesity is independently associated with larger heart chambers, greater left ventricle mass, and smaller left ventricle ejection fraction.enChildhood obesityEchocardiographyLeft ventricular ejection fractionLeft ventricular massAdolescentAdultBody mass indexCase-control studiesChildFemaleHumansMaleOverweightPediatric obesityStroke volumeVentricular function, leftresearch article35075570open accessFunción ventricular izquierdaNiñoObesidad infantilSobrepesoVolumen sistólicoÍndice de masa corporal10.1007/s00431-022-04384-01432-1076https://www.researchsquare.com/article/rs-921234/latest.pdf